Fast Facts: Myelofibrosis

Image of the book cover for 'Fast Facts: Myelofibrosis'
Author: Donal McLornan, MB BCH (Honours) PhD MRCP FRCPath, Claire Harrison, DM FRCP FRCPath
Publisher: Karger
Publication Date: 2022
ISBN 10: 3318070807
ISBN 13: 9783318070804
eISBN: 9783318071092
Edition: 1st
Myelofibrosis is a myeloproliferative neoplasm that has markedly heterogeneous features. The clinical phenotype can range from initial indolent presentation, which may be stable for many years, through to marked cytopenias, debilitating constitutional symptoms, massive splenomegaly and an inherent risk of leukemic transformation. Despite many advances regarding molecular classification, prognostication models and rapeutic options over the last few decades, allogeneic stem cell transplantation remains the only curative option, yet is suitable only for a minority of patients. 'Fast Facts: Myelofibrosis' is written for health professionals by two leading experts in the field, and provides up-to-date guidance on its accurate diagnosis, risk stratification and management. It also provides key insights into the molecular biology underpinning the disease. This concise handbook is an indispensable read for anyone wanting to get up to speed with best practice in the diagnosis and care of people with myelofibrosis.
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