ENHANZE Drug Delivery Technology Advancing Subcutaneous Drug Delivery using Recombinant Human Hyaluronidase PH20

Image of the book cover for 'ENHANZE Drug Delivery Technology'
Author: David Kang, Renee Tannenbaum, Beate Bittner, Kenneth Locke, Daniel Maneval, Bruno Flamion, Robert Connor, Michael LaBarre, Rose Sekulovich, Jean Cui, Marie Printz, Richard Wasserman, Saad Usmani
Publisher: Karger
Publication Date: 2022
ISBN 10: 3318070769
ISBN 13: 9783318070767
eISBN: 9783318070873
Edition: 1st
'ENHANZE drug delivery technology: Advancing subcutaneous drug delivery using recombinant human hyaluronidase PH20' provides readers with in-depth information on the potential benefits and challenges of subcutaneous (SC) drug delivery, the biology of hyaluronan and hyaluronidases in the SC space, and a comprehensive overview on the history of hyaluronidases and the development of recombinant human hyaluronidase PH20 (rHuPH20). Current applications of rHuPH20 as well as approved biotherapeutics utilizing HuPH20-facilitated SC drug delivery are summarized, and the underlying non-clinical and clinical development approaches are introduced as a basis for future application to biologics in various disease areas.
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