Fast Facts: Chronic Lymphocytic Leukemia

Image of the book cover for 'Fast Facts: Chronic Lymphocytic Leukemia'
Author: Toby Eyre, MBChB DipMedEd MRCP FRCPath MD, Parag Jasani, MBBS FRCP FRCPath, Lindsey Roeker, MD
Affiliation:
Publisher: Karger
Publication Date: 2022
ISBN 10: 3318069736
ISBN 13: 9783318069730
eISBN: 9783318069747
Edition: 1st
Description:
Chronic lymphocytic leukemia (CLL) is the most diagnosed leukemia in the Western world, accounting for approximately 25% of all new leukemia diagnoses. In recent years, remarkable progress has been made in our understanding of both the pathophysiology and genetics of CLL. While the disease generally affects older adults and initially follows an indolent course, cytogenetic and molecular profiling have helped to predict clinical outcomes. Greater prognostication, alongside the development of an increasing armamentarium of novel targeted therapies, has enabled us to provide more personalized management options for patients. 'Fast Facts: Chronic Lymphocytic Leukemia' covers the epidemiology, etiology, diagnosis and staging of the disease, and the molecular and genetic aspects that underpin treatment and prognosis. It provides a concise overview of treatment options, in both the front-line and relapsed/refractory settings, with particular focus on the novel targeted agents that have overcome many adverse prognostic factors, improving overall survival.
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