This handbook explores the challenges faced by physicians in the diagnosis and treatment of type 2 diabetes. Chapters dedicated to recommended interventions in plasma-glucose control, dyslipidemia, and diabetic nephropathy are featured along with discussions of lifestyle and behavior modifications and the signs and symptoms of new-onset diabetes. The latest data from the ACCORD and ADVANCE trials are in the second edition of the handbook as well as the advances in w-3 fatty acid and triglyceride-lowering therapy.