CLINICAL CHEMISTRY This title has been archived.

Author: Wendy Arneson, MS, MT(ASCP), Jean Brickell, EdD, MT(ASCP)
Affiliation: University of Oklahoma, Tulsa
Publisher: F.A. Davis Company
Publication Date: 2007
ISBN 10: 0803614985
ISBN 13: 9780803614987
Edition: 1st

Description:

Organized almost entirely around organ systems, this ground-breaking text teaches the concepts and principles of clinical chemistry through realistic situations and scenarios. The authors developed this practical approach to encourage students to apply theoretical principles in the laboratory and to develop practical, critical-thinking skills.

Table of Contents

Front Matter

  • ABOUT
  • DEDICATION
  • Preface
  • Acknowledgments
  • Reviewers
  • Contributors

Overview of Clinical Chemistry

  • OBJECTIVES
  • Clinical Chemistry Is a Service and an Industry
  • REGULATORY GUIDELINES
  • LICENSURE AND REGISTRY
  • Clinical Chemistry Is a Science
  • SUMMARY
  • EXERCISES
  • References

Quality Assessment

  • OBJECTIVES
  • QUALITY ASSESSMENT VERSUS QUALITY CONTROL
  • PREANALYTICAL ERRORS AND SPECIMEN PROBLEMS
  • POSTANALYTICAL FACTORS
  • SUMMARY
  • EXERCISES
  • References

Laboratory Techniques and Instrumentation

  • OBJECTIVES
  • HISTORY OF MEASUREMENT IN THE LABORATORY
  • MAKING THE DILUTION
  • DETERMINING MASS
  • INSTRUMENTATION
  • SPECTROPHOTOMETRY
  • OTHER PHOTOMETRIC TECHNIQUES
  • ANALYSIS WITH ELECTROCHEMISTRY
  • CHROMATOGRAPHY
  • IMMUNOASSAY TECHNIQUES
  • FUTURE INSTRUMENTATION PRINCIPLES IN CLINICAL CHEMISTRY
  • SUMMARY
  • EXERCISES
  • References

Diabetes and Other Carbohydrate Disorders

  • OBJECTIVES
  • DIABETES MELLITUS
  • LABORATORY RESULTS IN TYPE 1 DIABETES
  • GALACTOSEMIA
  • OTHER CARBOHYDRATE METABOLIC DISORDERS
  • QUALITY ASSURANCE
  • SUMMARY
  • EXERCISES
  • References

Hemoglobin Production Disorders and Testing

  • OBJECTIVES
  • HEME SYNTHESIS
  • ABSORPTION, TRANSPORT, AND STORAGE OF IRON
  • ASSESSING IRON LEVELS AND FORMS
  • MEASURING LEAD LEVELS
  • PORPHYRINS
  • GLYCATED HEMOGLOBIN
  • SUMMARY
  • EXERCISES
  • References

Assessment of Renal Function

  • OBJECTIVES
  • CREATININE METABOLISM
  • GLOMERULAR NEPHRITIS
  • NEPHROTIC SYNDROME
  • AZOTEMIA
  • TYPES AND ASPECTS OF RENAL FAILURE
  • CALCULATION OF FRACTIONAL EXCRETION OF SODIUM
  • RENAL CONTROL OF ACID-BASE BALANCE
  • THE ROLE OF ELECTROLYTES
  • RENAL TUBULAR ACIDOSIS
  • HEMOLYSIS
  • ELECTROLYTE ANALYSIS
  • RENAL IMPACT ON WATER AND ELECTROLYTES
  • PHYSIOLOGY: HORMONAL AND RENAL CONTROL OF ELECTROLYTES AND MINERALS
  • KIDNEY STONES
  • SUMMARY
  • EXERCISES
  • References

Assessment of Liver Function

  • OBJECTIVES
  • TESTS FOR LIVER FUNCTION
  • LIVER ANATOMY AND PHYSIOLOGY
  • BILIRUBIN METABOLISM
  • HYPERBILIRUBINEMIA
  • NEONATAL HYPERBILIRUBINEMIA
  • PATHOPHYSIOLOGY OF LIVER ENZYMES
  • ANALYTICAL ASPECTS OF LIVER ENZYMES
  • OTHER LABORATORY TEST RESULTS THAT CORRESPOND WITH LIVER DISORDERS
  • AMMONIA METABOLISM
  • CLINICAL SIGNIFICANCE OF ALKALINE PHOSPHATASE
  • SUMMARY
  • EXERCISES
  • References

Assessment of Cardiovascular Disorders

  • OBJECTIVES
  • THE FIRST THREE PATIENTS IN THE EMERGENCY DEPARTMENT
  • ACUTE MYOCARDIAL INFARCTION
  • LIPIDS AND LIPOPROTEINS
  • NATRIURETIC PEPTIDES
  • WHY WOMEN AND MEN EXPERIENCE DIFFERENT RISK FOR HEART ATTACKS
  • DELAYED DIAGNOSIS OF AMI
  • DIFFERENCES IN ELDERLY PATIENTS
  • SUMMARY
  • EXERCISES
  • References

Assessment of Respiratory Disorders

  • OBJECTIVES
  • COLLECTION AND HANDLING OF ARTERIAL BLOOD GASES
  • QUALITY ASSESSMENT AND IMPROVEMENT FOR ARTERIAL BLOOD GASES
  • ACID-BASE STATUS
  • VENTILATION AND PCO 2 RELATIONSHIP
  • OXYGENATION STATUS
  • RESPIRATORY DISORDERS
  • ANALYSIS OF OXYGENATION
  • TOXIC GASES
  • PROFICIENCY TESTING AND OTHER QUALITY ASSURANCE ISSUES
  • POINT-OF-CARE TESTING FOR BLOOD GASES
  • SUMMARY
  • EXERCISES
  • References

Assessment of Nutrition and Digestive Function

  • OBJECTIVES
  • Nutrition
  • Nutritional Disorders
  • Digestive Disorders
  • SUMMARY
  • EXERCISES
  • References

Endocrine Disorders and Function

  • OBJECTIVES
  • ENDOCRINOLOGY
  • THE PITUITARY GLAND
  • THE ADRENAL GLANDS
  • DISEASES OF THE ADRENAL CORTEX
  • SUMMARY OF ADRENAL CORTEX DISORDERS
  • ROLE OF ALDOSTERONE
  • GROWTH HORMONE
  • ADRENAL MEDULLARY HORMONES
  • DISORDERS OF ADRENAL MEDULLARY HORMONES
  • LABORATORY TESTING FOR ADRENAL MEDULLARY DISORDERS
  • ROLE OF ENDOCRINE GLANDS IN THYROID FUNCTION
  • TESTING FOR THYROID DISORDERS
  • HYPERTHYROIDISM
  • DISORDERS OF WATER BALANCE
  • MINERAL METABOLISM
  • PREANALYTICAL VARIATIONS IN HORMONE TESTING
  • SUMMARY
  • EXERCISES
  • References

Reproductive Endocrinology and Fetal Testing

  • OBJECTIVES
  • PREGNANCY
  • PREGNANCY TESTS AND EARLY MARKERS OF PROBLEMS
  • SEX STEROIDS
  • ENDOCRINE GLANDS INVOLVED IN REPRODUCTION
  • OVERVIEW OF NORMAL FEMALE REPRODUCTIVE PHYSIOLOGY
  • THE FEMALE REPRODUCTIVE CYCLE
  • NORMAL MALE REPRODUCTIVE PHYSIOLOGY
  • HORMONAL CHANGES IN MENOPAUSE
  • FEMALE INFERTILITY
  • QUALITY ASSESSMENT
  • ALPHA FETOPROTEIN
  • FETAL SCREENING
  • MULTIPLES OF THE MEDIAN
  • OTHER SIGNIFICANT BIRTH DEFECTS AND INBORN ERRORS OF METABOLISM
  • REFERENCE RANGES IN NEONATES
  • DEVELOPMENT OF HEMOLYTIC DISEASE OF THE NEWBORN
  • FETAL LUNG MATURITY
  • AMNIOTIC FLUID COLLECTION
  • TESTS FOR FETAL LUNG MATURITY
  • SUMMARY
  • EXERCISES
  • References

Malignancy Disorders and Testing

  • OBJECTIVES
  • LABORATORY TESTS TO SCREEN FOR DISEASE
  • TUMOR MARKERS FOR COLORECTAL CANCER
  • PROTEIN ELECTROPHORESIS
  • MULTIPLE MYELOMA
  • NEW TECHNIQUES TO HELP DIAGNOSIS OF MONOCLONAL GAMMOPATHIES
  • OTHER DISORDERS OF LYMPHOCYTES
  • CA 125
  • MEDICAL DECISION LIMITS
  • THE CELL CYCLE
  • MOLECULAR DIAGNOSTICS
  • PROSTATE CANCER
  • SODIUM AND WATER BALANCE
  • PANCREATIC CANCER
  • SUMMARY
  • EXERCISES
  • References

Therapeutic Drug Monitoring and Toxicology

  • OBJECTIVES
  • Therapeutic Drug Monitoring
  • Toxicology
  • SUMMARY
  • EXERCISES
  • References

Glossary

Appendix