Eyelid, Conjunctival, and Orbital Tumors

Author: Jerry Shields, MD, Carol Shields, MD
Publisher: Lippincott Williams & Wilkins
Publication Date: 2016
ISBN 10: 1496321480
ISBN 13: 9781496321480
eISBN: 9781496321497
Edition: 3rd


For outstanding visual clarity in ocular diagnosis ...nothing else comes close. In this updated and revised third edition, world-renowned authorities from the Wills Eye Hospital provide outstanding guidance on recognition, evaluation, and treatment of ocular tumors, highlighted by more than 3,000 stunning photographs and surgical drawings. This unsurpassed ocular oncology resource is a comprehensive guide to the clinical features, diagnosis, management, and pathology of eyelid, conjunctival, and orbital tumors and pseudotumors, depicting clinical variations, treatment and histopathologic characteristics of the wide spectrum of neoplasms and related lesions. Now brought thoroughly up to date with recent clinical and scientific innovations, this unique volume offers more high-quality images than any other text/atlas in the field. * Presents each entity in an easy-to-follow format: a concise description with references on the left-hand page and six illustrations on the right-hand page.

Table of Contents

Front Matter

  • Foreword 1
  • Foreword 2
  • Preface
  • Acknowledgments

PART 1 Tumors of The Eyelids

    CHAPTER 1: Benign Tumors of the Eyelid Epidermis

    • Eyelid Squamous Papilloma
    • Eyelid Seborrheic Keratosis
    • Eyelid Inverted Follicular Keratosis
    • Eyelid Pseudoepitheliomatous Hyperplasia
    • Eyelid Keratoacanthoma and Nonspecific Keratosis

    CHAPTER 2: Premalignant and Malignant Tumors of Eyelid Epidermis

    • Eyelid Actinic Keratosis
    • Radiation Blepharopathy
    • Eyelid Xeroderma Pigmentosum
    • Sebaceous Nevus
    • Eyelid Basal Cell Carcinoma
    • Eyelid Squamous Cell Carcinoma

    CHAPTER 3: Eyelid Sebaceous Gland Tumors

    • Eyelid Sebaceous Hyperplasia and Adenoma
    • Eyelid Sebaceous Carcinoma

    CHAPTER 4: Eyelid Sweat Gland Tumors

    • Eyelid Syringoma
    • Eyelid Eccrine Acrospiroma
    • Eyelid Syringocystadenoma Papilliferum
    • Eyelid Pleomorphic Adenoma (Benign Mixed Tumor)
    • Eyelid Sweat Gland Adenocarcinoma

    CHAPTER 5: Eyelid Hair Follicle Tumors

    • Eyelid Trichoepithelioma
    • Eyelid Trichofolliculoma and Trichoadenoma
    • Eyelid Trichilemmoma
    • Eyelid Pilomatrixoma

    CHAPTER 6: Eyelid Melanocytic Tumors

    • Eyelid Melanocytic Nevus
    • Oculodermal Melanocytosis (Nevus of Ota)
    • Eyelid Lentigo Maligna (Melanotic Freckle of Hutchinson)
    • Eyelid Blue Nevus
    • Eyelid Primary Malignant Melanoma

    CHAPTER 7: Neural Tumors of the Eyelid

    • Eyelid Neurofibroma
    • Eyelid Schwannoma (Neurilemoma) and Neurothekeoma
    • Eyelid Merkel Cell Carcinoma (Cutaneous Neuroendocrine Carcinoma)

    CHAPTER 8: Vascular Tumors of the Eyelids

    • Eyelid Congenital Capillary Hemangioma (Strawberry Hemangioma)
    • Eyelid Acquired Hemangioma (Cherry Hemangioma)
    • Eyelid Nevus Flammeus (Port Wine Hemangioma)
    • Eyelid Varix
    • Eyelid Lymphangioma
    • Eyelid Glomus Tumor
    • Eyelid Kaposi’s Sarcoma
    • Eyelid Angiosarcoma

    CHAPTER 9: Eyelid Lymphoid, Plasmacytic, and Metastatic Tumors

    • Eyelid Lymphoma
    • Eyelid Plasmacytoma
    • Metastatic Neoplasms to the Eyelids

    CHAPTER 10: Eyelid Histiocytic, Myxoid, and Fibrous Lesions

    • Eyelid Xanthelasma and Xanthoma
    • Eyelid Xanthogranuloma
    • Eyelid Necrobiotic Xanthogranuloma with Paraproteinemia
    • Eyelid Angiofibroma
    • Eyelid Nodular Fasciitis
    • Eyelid Miscellaneous Fibrous and Myxomatous Tumors

    CHAPTER 11: Eyelid Cystic Lesions Simulating Neoplasms

    • Eyelid Eccrine Hidrocystoma
    • Eyelid Apocrine Hidrocystoma
    • Eyelid Sebaceous Cyst (Pilar Cyst)
    • Eyelid Epidermal Inclusion Cyst (Epidermoid Cyst)
    • Eyelid Dermoid Cyst

    CHAPTER 12: Eyelid Inflammatory Lesions Simulating Neoplasms

    • Eyelid Molluscum Contagiosum Infection
    • Eyelid Chalazion
    • Miscellaneous Granulomatous Diseases
    • Eyelid Mycotic Infections
    • Eyelid Bacterial Infections

    CHAPTER 13: Eyelid Miscellaneous Conditions Simulating Neoplasms

    • Eyelid Amyloidosis
    • Eyelid Lipoid Proteinosis (Urbach–Wiethe Disease)
    • Miscellaneous Other Pseudoneoplastic Eyelid Lesions
    • Eyelid Phakomatous Choristoma

    CHAPTER 14: Tumors of the Lacrimal Drainage System

    • Lacrimal Drainage System Tumors
    • Lacrimal Sac Squamous Papilloma and Carcinoma
    • Lacrimal Sac Melanoma
    • Lacrimal Sac: Miscellaneous Tumors and Pseudotumors

    CHAPTER 15: Surgical Management of Eyelid Tumors

    • Surgical Management of Eyelid Tumors

PART 2 Tumors of the Conjunctiva

    CHAPTER 16: Conjunctival and Epibulbar Choristomas

    • Conjunctival Dermoid
    • Conjunctival/Orbital Dermolipoma
    • Epibulbar Osseous Choristoma
    • Lacrimal Gland and Respiratory Choristomas of Conjunctiva
    • Conjunctival Complex Choristoma

    CHAPTER 17: Conjunctival Benign Epithelial Tumors

    • Conjunctival Papilloma of Childhood
    • Conjunctival Papilloma of Adulthood
    • Conjunctival Pseudoepitheliomatous Hyperplasia and Keratoacanthoma
    • Conjunctival Hereditary Benign Intraepithelial Dyskeratosis
    • Conjunctival Dacryoadenoma

    CHAPTER 18: Premalignant and Malignant Lesions of the Conjunctival Epithelium

    • Conjunctival Keratotic Plaque and Actinic Keratosis
    • Conjunctival Intraepithelial Neoplasia
    • Conjunctival Invasive Squamous Cell Carcinoma

    CHAPTER 19: Conjunctival Melanocytic Lesions

    • Conjunctival Melanocytic Nevus
    • Ocular Melanocytosis: Scleral and Episcleral Pigment
    • Complexion-Related Conjunctival Pigmentation (Complexion-Associated Melanosis, Racial Melanosis)
    • Conjunctival Primary Acquired Melanosis
    • Conjunctival Malignant Melanoma

    CHAPTER 20: Vascular Tumors and Related Lesions of the Conjunctiva

    • Conjunctival Pyogenic Granuloma
    • Conjunctival Lymphangiectasia and Lymphangioma
    • Miscellaneous Vascular Lesions of the Conjunctiva: Varix, Cavernous Hemangioma, Macrovessels, Sentinel Vessels, and Acquired Sessile Hemangioma
    • Conjunctival Acquired Sessile Hemangioma and Capillary Hemangioma
    • Conjunctival Hemangiopericytoma and Glomangioma (Glomus Tumor)
    • Conjunctival Kaposi Sarcoma

    CHAPTER 21: Conjunctival Neural, Xanthomatous, Fibrous, Myxomatous, and Lipomatous Tumors

    • Conjunctival Neuroma and Neurofibroma
    • Conjunctival Schwannoma and Granular Cell Tumor
    • Conjunctival Fibrous Histiocytoma
    • Conjunctival Miscellaneous Lesions: Fibroma, Nodular Fasciitis, and Juvenile Xanthogranuloma
    • Conjunctival Miscellaneous Lesions: Myxoma, Lipoma, and Reticulohistiocytoma

    CHAPTER 22: Conjunctival Lymphoid, Leukemic, and Metastatic Tumors

    • Conjunctival Lymphoid and Plasmacytic Tumors
    • Conjunctival Posttransplant Lymphoproliferative Disorder
    • Conjunctival Leukemia
    • Conjunctival Metastatic Tumors

    CHAPTER 23: Caruncular Tumors

    • Caruncular Tumors

    CHAPTER 24: Miscellaneous Lesions that Simulate Conjunctival Neoplasms

    • Conjunctival Epithelial Inclusion Cyst
    • Conjunctival Organizing Hematoma (“Hematic Cyst”; “Hematocele”)
    • Conjunctival Foreign Body
    • Episcleritis and Scleritis Simulating Neoplasms
    • Conjunctival Churg–Strauss Allergic Granulomatosis Simulating Conjunctival Neoplasm
    • Conjunctival Ligneous Conjunctivitis
    • Conjunctival Miscellaneous Infectious Lesions that Simulate Neoplasms
    • Conjunctival Amyloidosis
    • Pinguecula
    • Pterygium
    • Conjunctival and Scleral Miscellaneous Lesions that Simulate Pigmented Melanoma

    CHAPTER 25: Surgical Management of Conjunctival Tumors

    • Surgical Management of Conjunctival Tumors

PART 3 Tumors of the Orbit

    CHAPTER 26: Inflammatory Orbital Lesions that Simulate Neoplasms

    • Thyroid-Related Ophthalmopathy
    • Orbital Cellulitis
    • Orbit: Idiopathic Nongranulomatous Orbital Inflammation (Inflammatory Pseudotumor, Idiopathic Orbital Inflammatory Syndrome)
    • Immunoglobulin G4–Related Disease (IgG4-RD)
    • Orbital Tuberculosis
    • Orbital Mycotic Infections: Aspergillosis and Mucormycosis
    • Orbital Aspergillosis—Allergic Fungal Sinusitis
    • Orbital Sarcoidosis
    • Orbital Granulomatosis with Polyangiitis (Wegener Granulomatosis)
    • Kimura Disease and Angiolymphoid Hyperplasia with Eosinophilia

    CHAPTER 27: Orbital Cystic Lesions

    • Orbital Dermoid Cyst
    • Orbital Simple Primary Cyst of Conjunctival Origin
    • Orbital Teratoma (Teratomatous Cyst)
    • Orbital Congenital Cystic Eye
    • Orbital Colobomatous Cyst (Microphthalmos with Cyst)
    • Orbital Cephalocele
    • Orbital Mucocele
    • Orbital Respiratory Epithelial Cyst
    • Orbital Parasitic Cysts

    CHAPTER 28: Orbital Vascular and Hemorrhagic Lesions

    • Orbital Capillary Hemangioma
    • Orbital Cavernous Hemangioma
    • Orbital Hemangiopericytoma
    • Orbital Lymphangioma
    • Orbital Varix
    • Orbital Miscellaneous Vascular Lesions: Intravascular Papillary Endothelial Hyperplasia and Glomus Tumor of the Orbit
    • Orbital Angiosarcoma
    • Orbital Hematoma

    CHAPTER 29: Orbital Peripheral Nerve Tumors

    • Orbital (Neurilemoma)
    • Orbital Neurofibroma
    • Orbital Paraganglioma (Chemodectoma)
    • Orbital Alveolar Soft Part Sarcoma
    • Miscellaneous Orbital Neural Tumors: Granular Cell Tumor, Amputation Neuroma, and Malignant Peripheral Nerve Sheath Tumor

    CHAPTER 30: Optic Nerve, Meningeal, and Other Neural Tumors

    • Optic Nerve Juvenile Pilocytic Astrocytoma (Optic Nerve Glioma)
    • Optic Nerve Malignant Astrocytoma
    • Optic Nerve Sheath Meningioma
    • Orbital Sphenoid Wing Meningioma
    • Orbital Primitive Neuroectodermal Tumor and Primary Orbital Neuroblastoma

    CHAPTER 31: Orbital Myogenic Tumors

    • Orbital Rhabdomyosarcoma
    • Orbital Malignant Rhabdoid Tumor
    • Orbital Leiomyoma
    • Orbital Leiomyosarcoma

    CHAPTER 32: Orbital Fibrous Connective Tissue Tumors

    • Orbital Nodular Fasciitis and Fibroma
    • Orbital Fibromatosis, Myofibromatosis, and Myofibroma
    • Orbital Fibrous Histiocytoma
    • Orbital Solitary Fibrous Tumor
    • Orbital Fibrosarcoma

    CHAPTER 33: Orbital Osseous, Fibro-osseous, and Cartilaginous Tumors

    • Orbital Osteoma
    • Orbit Osteosarcoma
    • Orbital Fibrous Dysplasia
    • Orbital Ossifying Fibroma
    • Orbital Giant Cell Reparative Granuloma
    • Orbital Cartilaginous Chondroma
    • Orbital Chondrosarcoma

    CHAPTER 34: Orbital Lipomatous and Myxomatous Tumors

    • Orbital Fat Prolapse
    • Orbital/Conjunctival Dermolipoma
    • Orbital Lipoma and Myxoma
    • Orbital Myxoma
    • Orbital Liposarcoma

    CHAPTER 35: Orbital Histiocytic Tumors

    • Orbit Juvenile Xanthogranuloma
    • Orbital Langerhans’ Cell Histiocytosis (Eosinophilic Granuloma)
    • Orbital Erdheim–Chester Disease
    • Orbital Rosai–Dorfman Disease (Sinus Histiocytosis with Massive Lymphadenopathy)
    • Necrobiotic Xanthogranuloma and Multinucleate Cell Angiohistiocytoma

    CHAPTER 36: Orbital Primary Melanocytic Tumors

    • Orbital Melanoma Arising from Ocular Melanocytosis and Blue Nevus
    • Orbital Melanomas Arising de Novo
    • Orbital Melanocytic Hamartoma and Melanotic Neuroectodermal Tumor

    CHAPTER 37: Lacrimal Gland Primary Epithelial Tumors

    • Introduction: Lacrimal Gland Lesions
    • Lacrimal Gland Ductal Epithelial Cyst (Dacryops)
    • Lacrimal Gland Pleomorphic Adenoma (Benign Mixed Tumor)
    • Lacrimal Gland Pleomorphic Adenocarcinoma
    • Lacrimal Gland Adenoid Cystic Carcinoma
    • Lacrimal Gland Primary Ductal Carcinoma
    • Histopathology of Primary Epithelial Malignancies of Lacrimal Gland

    CHAPTER 38: Orbital Metastatic Cancer

    • Orbital Metastatic Cancer

    CHAPTER 39: Orbital Lymphoid Tumors and Leukemias

    • Orbital Non-Hodgkin Lymphoma
    • Orbital Lymphoma: Atypical Forms
    • Orbital Plasmacytoma and Lymphoplasmacytoid Tumors
    • Orbital Plasmablastic Lymphoma
    • Orbital Burkitt Lymphoma
    • Orbital Post-Transplant Lymphoproliferative Disorder
    • Orbital–Orbital Involvement by Leukemia (Myeloid Sarcoma)

    CHAPTER 40: Orbital Secondary Tumors

    • Orbital Secondary Tumors

    CHAPTER 41: Surgical Management of Orbital Tumors

    • Surgical Management of Orbital Tumors