THE DEVELOPING HUMAN

Author: Keith Moore, MSc, PhD, FIAC, FRSM, FAAA, T. Persaud, MD, PhD, DSc, FRCPath (Lond.), FAAA, Mark Torchia, MSc, PhD
Affiliation: University of Toronto, Canada
Publisher: Elsevier Health Sciences
Publication Date: 2013
ISBN 10: 1437720021
ISBN 13: 9781437720020
Edition: 9th

Description:

The Developing Human: Clinically Oriented Embryology, by Drs. Keith L. Moore, T.V.N. Persaud, and Mark G. Torchia, delivers the world's most complete, visually rich, and clinically oriented coverage of this complex subject. Written by some of the world's most famous anatomists, it presents week-by-week and stage-by-stage views of how fetal organs and systems develop, why and when birth defects occur, and what roles the placenta and fetal membranes play in development. You can also access the complete contents online at www.studentconsult.com, along with 17 remarkable animations, downloadable illustrations, additional review questions and answers, and more.

Table of Contents

Front Matter

  • ABOUT
  • About the Authors
  • Notices
  • DEDICATION
  • Contributors
  • Preface
  • Acknowledgments

Introduction to the Developing Human

  • DEVELOPMENTAL PERIODS
  • SIGNIFICANCE OF EMBRYOLOGY
  • HISTORICAL GLEANINGS
  • GENETICS AND HUMAN DEVELOPMENT
  • MOLECULAR BIOLOGY OF HUMAN DEVELOPMENT
  • DESCRIPTIVE TERMS IN EMBRYOLOGY
  • CLINICALLY ORIENTED PROBLEMS
  • REFERENCES AND SUGGESTED READINGS

First Week of Human Development

  • GAMETOGENESIS
  • MEIOSIS
  • SPERMATOGENESIS
  • OOGENESIS
  • COMPARISON OF GAMETES (SEX CELLS)
  • UTERUS, UTERINE TUBES, AND OVARIES
  • FEMALE REPRODUCTIVE CYCLES
  • OVARIAN CYCLE
  • MENSTRUAL CYCLE
  • TRANSPORTATION OF GAMETES
  • MATURATION OF SPERMS
  • VIABILITY OF GAMETES
  • FERTILIZATION
  • CLEAVAGE OF ZYGOTE
  • FORMATION OF BLASTOCYST
  • SUMMARY OF FIRST WEEK (FIG. 2-20)
  • CLINICALLY ORIENTED PROBLEMS
  • REFERENCES AND SUGGESTED READING

Second Week of Human Development

  • COMPLETION OF IMPLANTATION OF BLASTOCYST
  • FORMATION OF AMNIOTIC CAVITY, EMBRYONIC DISC, AND UMBILICAL VESICLE
  • DEVELOPMENT OF CHORIONIC SAC
  • IMPLANTATION SITES OF BLASTOCYSTS
  • SUMMARY OF IMPLANTATION
  • SUMMARY OF SECOND WEEK
  • CLINICALLY ORIENTED PROBLEMS
  • REFERENCES AND SUGGESTED READING

Third Week of Human Development

  • GASTRULATION: FORMATION OF GERM LAYERS
  • PRIMITIVE STREAK
  • NOTOCHORDAL PROCESS AND NOTOCHORD
  • ALLANTOIS
  • NEURULATION: FORMATION OF NEURAL TUBE
  • DEVELOPMENT OF SOMITES
  • DEVELOPMENT OF INTRAEMBRYONIC COELOM
  • EARLY DEVELOPMENT OF CARDIOVASCULAR SYSTEM
  • DEVELOPMENT OF CHORIONIC VILLI
  • SUMMARY OF THIRD WEEK
  • CLINICALLY ORIENTED PROBLEMS
  • REFERENCES AND SUGGESTED READING

Fourth to Eighth Weeks of Human Development

  • PHASES OF EMBRYONIC DEVELOPMENT
  • FOLDING OF EMBRYO
  • GERM LAYER DERIVATIVES
  • CONTROL OF EMBRYONIC DEVELOPMENT
  • HIGHLIGHTS OF FOURTH TO EIGHTH WEEKS
  • ESTIMATION OF EMBRYONIC AGE
  • SUMMARY OF FOURTH TO EIGHTH WEEKS
  • CLINICALLY ORIENTED PROBLEMS
  • REFERENCES AND SUGGESTED READING

Ninth Week to Birth: The Fetal Period

  • ESTIMATION OF FETAL AGE
  • HIGHLIGHTS OF FETAL PERIOD
  • EXPECTED DATE OF DELIVERY
  • FACTORS INFLUENCING FETAL GROWTH
  • PROCEDURES FOR ASSESSING FETAL STATUS
  • SUMMARY OF FETAL PERIOD
  • CLINICALLY ORIENTED PROBLEMS
  • REFERENCES AND SUGGESTED READING

Placenta and Fetal Membranes

  • PLACENTA
  • PARTURITION
  • UMBILICAL VESICLE
  • ALLANTOIS
  • MULTIPLE PREGNANCIES
  • SUMMARY OF PLACENTA AND FETAL MEMBRANES
  • CLINICALLY ORIENTED PROBLEMS
  • REFERENCES AND SUGGESTED READING

Body Cavities and Diaphragm

  • EMBRYONIC BODY CAVITY
  • DEVELOPMENT OF THE DIAPHRAGM
  • SUMMARY OF DEVELOPMENT OF THE BODY CAVITIES AND DIAPHRAGM
  • CLINICALLY ORIENTED PROBLEMS
  • REFERENCES AND SUGGESTED READING

Pharyngeal Apparatus, Face, and Neck

  • PHARYNGEAL ARCHES
  • PHARYNGEAL POUCHES
  • PHARYNGEAL GROOVES
  • PHARYNGEAL MEMBRANES
  • DEVELOPMENT OF THYROID GLAND
  • DEVELOPMENT OF TONGUE
  • DEVELOPMENT OF SALIVARY GLANDS
  • DEVELOPMENT OF FACE
  • SUMMARY OF FACIAL DEVELOPMENT
  • DEVELOPMENT OF NASAL CAVITIES
  • DEVELOPMENT OF PALATE
  • SUMMARY OF PHARYNGEAL APPARATUS, FACE, AND NECK
  • CLINICALLY ORIENTED PROBLEMS
  • REFERENCES AND SUGGESTED READING

Respiratory System

  • RESPIRATORY PRIMORDIUM
  • DEVELOPMENT OF LARYNX
  • DEVELOPMENT OF TRACHEA
  • DEVELOPMENT OF BRONCHI AND LUNGS
  • SUMMARY OF RESPIRATORY SYSTEM
  • CLINICALLY ORIENTED PROBLEMS
  • REFERENCES AND SUGGESTED READING

Alimentary System

  • FOREGUT
  • MIDGUT
  • HINDGUT
  • SUMMARY OF ALIMENTARY SYSTEM
  • CLINICALLY ORIENTED PROBLEMS
  • REFERENCES AND SUGGESTED READING

Urogenital System

  • DEVELOPMENT OF URINARY SYSTEM
  • DEVELOPMENT OF SUPRARENAL GLANDS
  • DEVELOPMENT OF GENITAL SYSTEM
  • DEVELOPMENT OF EXTERNAL GENITALIA
  • DEVELOPMENT OF INGUINAL CANALS
  • RELOCATION OF TESTES AND OVARIES
  • SUMMARY OF UROGENITAL SYSTEM
  • CLINICALLY ORIENTED PROBLEMS
  • REFERENCES AND SUGGESTED READING

Cardiovascular System

  • EARLY DEVELOPMENT OF THE HEART AND BLOOD VESSELS
  • LATER DEVELOPMENT OF THE HEART
  • BIRTH DEFECTS OF THE HEART AND GREAT VESSELS
  • DERIVATIVES OF PHARYNGEAL ARCH ARTERIES
  • FETAL AND NEONATAL CIRCULATION
  • DEVELOPMENT OF LYMPHATIC SYSTEM
  • SUMMARY OF CARDIOVASCULAR SYSTEM
  • CLINICALLY ORIENTED PROBLEMS
  • REFERENCES AND SUGGESTED READING

Skeletal System

  • DEVELOPMENT OF BONE AND CARTILAGE
  • DEVELOPMENT OF JOINTS
  • DEVELOPMENT OF AXIAL SKELETON
  • DEVELOPMENT OF APPENDICULAR SKELETON
  • SUMMARY OF SKELETAL SYSTEM
  • CLINICALLY ORIENTED PROBLEMS
  • REFERENCES AND SUGGESTED READING

Muscular System

  • DEVELOPMENT OF SKELETAL MUSCLE
  • DEVELOPMENT OF SMOOTH MUSCLE
  • DEVELOPMENT OF CARDIAC MUSCLE
  • SUMMARY OF MUSCULAR SYSTEM
  • CLINICALLY ORIENTED PROBLEMS
  • REFERENCES AND SUGGESTED READING

Development of Limbs

  • EARLY STAGES OF LIMB DEVELOPMENT
  • FINAL STAGES OF LIMB DEVELOPMENT
  • BIRTH DEFECTS OF LIMBS
  • SUMMARY OF LIMB DEVELOPMENT
  • CLINICALLY ORIENTED PROBLEMS
  • REFERENCES AND SUGGESTED READING

Nervous System

  • DEVELOPMENT OF NERVOUS SYSTEM
  • DEVELOPMENT OF SPINAL CORD
  • DEVELOPMENT OF BRAIN
  • BIRTH DEFECTS OF BRAIN
  • DEVELOPMENT OF PERIPHERAL NERVOUS SYSTEM
  • DEVELOPMENT OF AUTONOMIC NERVOUS SYSTEM
  • SUMMARY OF NERVOUS SYSTEM
  • CLINICALLY ORIENTED PROBLEMS
  • REFERENCES AND SUGGESTED READING

Development of Eyes and Ears

  • DEVELOPMENT OF EYES AND RELATED STRUCTURES
  • DEVELOPMENT OF EARS
  • SUMMARY OF DEVELOPMENT OF EYES
  • SUMMARY OF DEVELOPMENT OF EARS
  • CLINICALLY ORIENTED PROBLEMS
  • REFERENCES AND SUGGESTED READING

Integumentary System

  • DEVELOPMENT OF SKIN AND APPENDAGES
  • SUMMARY OF INTEGUMENTARY SYSTEM
  • CLINICALLY ORIENTED PROBLEMS
  • REFERENCES AND SUGGESTED READING

Human Birth Defects

  • CLASSIFICATION OF BIRTH DEFECTS
  • TERATOLOGY: STUDY OF ABNORMAL DEVELOPMENT
  • BIRTH DEFECTS CAUSED BY GENETIC FACTORS
  • BIRTH DEFECTS CAUSED BY ENVIRONMENTAL FACTORS
  • BIRTH DEFECTS CAUSED BY MULTIFACTORIAL INHERITANCE
  • SUMMARY OF HUMAN BIRTH DEFECTS
  • CLINICALLY ORIENTED PROBLEMS
  • REFERENCES AND SUGGESTED READING

Common Signaling Pathways Used During Development

  • INTERCELLULAR COMMUNICATION
  • MORPHOGENS
  • RECEPTOR TYROSINE KINASES
  • NOTCH-DELTA PATHWAY
  • TRANSCRIPTION FACTORS
  • EPIGENETICS
  • STEM CELLS: DIFFERENTIATION VERSUS PLURIPOTENCY
  • SUMMARY OF COMMON SIGNALING PATHWAYS USED DURING DEVELOPMENT
  • REFERENCES AND SUGGESTED READING

Appendix Discussion of Clinically Oriented Problems