CANCER NURSING Principles and Practice

Author: Connie Yarbro, MS, RN, FAAN, Debra Wujcik, PhD, RN, AOCN®, Barbara Gobel, MS, RN, AOCN®
Affiliation: Adjunct Clinical Professor, University of Missouri Sinclair School of Nursing, Columbia, Missouri, Editor, Seminars in Oncology Nursing
Publisher: Jones & Bartlett Learning
Publication Date: 2011
ISBN 10: 0763763578
ISBN 13: 9780763763572
Edition: 7th

Description:

A new and revised version of this best-selling reference! For over eighteen years, best-selling Cancer Nursing: Principles and Practice has provided oncology nurses with the latest information on new trends in the rapidly changing science of oncology. Now, in its Seventh Edition, Cancer Nursing has been completely revised and updated to reflect key new developments. New topics covered include targeted therapy, hypersensitivity reactions, mucositis, and family and caregiver issues. With 27 new chapters featuring insights from key authors, the Seventh Edition is a must-have resource for every oncology nurse.

Table of Contents

Front Matter

  • ABOUT
  • Preface
  • The Editors
  • Contributors

PART I The Cancer Problem

    Biology of Cancer

    • INTRODUCTION
    • THEORIES AND RESEARCH MODELS OF TUMOR DEVELOPMENT
    • PROPERTIES OF CANCER AND TRANSFORMED CELLS
    • GENETIC INFLUENCES ASSOCIATED WITH CANCER
    • THE CELL CYCLE
    • APOPTOSIS
    • METASTASIS
    • CONCLUSION
    • REFERENCES

    Immunology

    • INTRODUCTION
    • OVERVIEW
    • COMPONENTS OF THE IMMUNE SYSTEM
    • MECHANISMS OF ADAPTIVE IMMUNITY
    • TISSUE DESTRUCTION FROM IMMUNE RESPONSES
    • FACTORS AFFECTING IMMUNE RESPONSES
    • IMPLICATIONS FOR NURSING PRACTICE
    • REFERENCES

    Epidemiology

    • INTRODUCTION
    • BASIC CONSIDERATIONS IN EPIDEMIOLOGICAL RESEARCH
    • CAUSES OF CANCER
    • BIOMARKERS
    • HOST CHARACTERISTICS INFLUENCING CANCER SUSCEPTIBILITY
    • PSYCHONEUROIMMUNOLOGY AND CANCER RISK
    • APPLICATION OF EPIDEMIOLOGY TO NURSING PRACTICE
    • REFERENCES

PART II Prevention, Detection, and Diagnosis

    Cultural Diversity Among Individuals With Cancer

    • INTRODUCTION
    • ETHNICITY AND CANCER
    • NURSING ISSUES
    • RESOURCES
    • CONCLUSION
    • ACKNOWLEDGMENT
    • REFERENCES

    Dynamics of Cancer Prevention

    • INTRODUCTION
    • CANCER PREVENTION PRINCIPLES
    • CANCER PREVENTION STRATEGIES
    • CANCER PREVENTION AND PUBLIC POLICY
    • CANCER PREVENTION CHALLENGES
    • NURSING IMPLICATIONS
    • REFERENCES

    Screening and Detection for Asymptomatic Individuals

    • INTRODUCTION
    • CONCEPTUAL CONSIDERATIONS IN CANCER SCREENING
    • CANCER RISK ASSESSMENT: THE FIRST STEP IN THE CANCER SCREENING PROCESS
    • ORAL COMMUNICATION OF RISK
    • MEASURES OF THE ACCURACY OF SCREENING TESTS
    • IMPLEMENTING CANCER SCREENING
    • NURSING IMPLICATIONS
    • CONCLUSION
    • REFERENCES

    Genetic Risk and Hereditary Cancer Syndromes

    • INTRODUCTION
    • CANCER NURSING PRACTICE AND HEREDITARY CANCER SYNDROMES
    • VOCABULARY OF HEREDITARY CANCER SYNDROMES FOR ONCOLOGY NURSES
    • CHARACTERISTICS OF HEREDITARY CANCER SYNDROMES
    • ETHICAL, LEGAL, AND SOCIAL IMPLICATIONS OF PREDISPOSITION GENETIC TESTING FOR HEREDITARY CANCER SYNDROMES
    • RISK ASSESSMENT OF CANCER SUSCEPTIBILITY
    • CANCER RISK ASSESSMENT MODELS
    • GENETIC COUNSELING
    • SELECTED HEREDITARY CANCER SYNDROMES
    • CONCLUSION
    • REFERENCES
    • APPENDIX 7-1 Cancer Genetics Resources: An Organizational Guide

    Diagnostic Evaluation, Classification, and Staging

    • INTRODUCTION
    • GOALS AND FACTORS AFFECTING THE DIAGNOSTIC APPROACH
    • THE DIAGNOSTIC APPROACH
    • CLASSIFICATION AND NOMENCLATURE
    • STAGING AND GRADING CLASSIFICATIONS
    • NURSING IMPLICATIONS
    • FUTURE TRENDS
    • CONCLUSION
    • REFERENCES

PART III Treatment

    Quality of Life as an Outcome of Cancer Care

    • INTRODUCTION
    • QUALITY OF LIFE AS A PROGNOSTIC INDICATOR
    • USING QUALITY OF LIFE INFORMATION IN CANCER CARE
    • USING QUALITY OF LIFE QUESTIONNAIRES IN CLINICAL PRACTICE
    • WHAT IS QUALITY OF LIFE?
    • MEASURING QUALITY OF LIFE
    • CLINICAL SIGNIFICANCE
    • DATA COLLECTION IN REAL TIME
    • POPULATIONS PRESENTING SPECIAL CHALLENGES
    • CONCLUSION
    • REFERENCES

    Principles of Cancer Clinical Trials

    • OVERVIEW
    • THE CLINICAL TRIALS PROCESS AND IMPLEMENTATION
    • NONCLINICAL TRIAL ACCESS TO EXPERIMENTAL AGENTS: SPECIAL ACCESS PROGRAMS
    • PROTECTION OF RESEARCH PARTICIPANTS
    • DATA MONITORING COMMITTEE
    • BARRIERS TO CLINICAL TRIALS PARTICIPATION
    • CANCER CLINICAL TRIALS PROGRAMS
    • CURRENT ISSUES
    • FUTURE TRENDS
    • REFERENCES

    Surgical Therapy

    • INTRODUCTION
    • ROLES OF SURGERY IN ONCOLOGY CARE
    • CLINICAL DECISION MAKING IN SURGICAL THERAPY
    • IMPACT OF NURSING CARE ON SURGICAL OUTCOMES
    • TRENDS IN SURGICAL ONCOLOGY
    • SPECIAL CONSIDERATIONS FOR NURSING CARE
    • CONCLUSION
    • REFERENCES

    Principles of Radiation Therapy

    • INTRODUCTION
    • HISTORY OF RADIATION THERAPY
    • GOALS OF TREATMENT APPROACHES
    • APPLIED RADIATION PHYSICS
    • HIGH-LINEAR-ENERGY-TRANSFER AND CHARGED-PARTICLE RADIATION THERAPY
    • RADIOBIOLOGY
    • CHEMICAL AND THERMAL MODIFIERS OF RADIATION
    • I NCIDENTAL AND ACCIDENTAL RADIATION EXPOSURE
    • CONCLUSION
    • REFERENCES

    Radiation Treatment Planning

    • INTRODUCTION
    • OVERVIEW
    • SIMULATION
    • PLANNING/LOCALIZATION/IMAGING
    • PRINCIPLES OF EXTERNAL BEAM RADIATION DOSING/DOSIMETRY
    • PATIENT POSITIONING AND IMMOBILIZATION TECHNIQUES
    • DELIVERY OF RADIATION THERAPY: MACHINES AND EQUIPMENT
    • TREATMENT DELIVERY MODALITIES
    • ADVANCED TOPICS: TREATMENT DELIVERY
    • CONCLUSION
    • REFERENCES

    Radiation Therapy: Toxicities and Management

    • INTRODUCTION
    • RADIOBIOLOGY
    • TISSUE AND ORGAN RESPONSE TO RADIATION
    • ROLES OF NURSING IN RADIATION ONCOLOGY
    • GENERAL SIDE EFFECTS OF RADIATION
    • ACUTE RADIATION TOXICITIES AND MANAGEMENT: SITE SPECIFIC
    • SECONDARY MALIGNANCIES
    • CONCLUSION
    • REFERENCES

    Cytotoxic Chemotherapy: Principles of Therapy

    • HISTORICAL PERSPECTIVE
    • CANCER CHEMOTHERAPY DRUG DEVELOPMENT
    • SCIENTIFIC BASIS OF CHEMOTHERAPY
    • CYTOTOXIC DRUG-SELECTION CRITERIA
    • MANAGING CHEMOTHERAPY RESISTANCE
    • CHEMOTHERAPY AS A TREATMENT FOR CANCER
    • PHARMACOLOGY OF CHEMOTHERAPEUTIC DRUGS
    • CONCLUSION
    • REFERENCES

    Chemotherapy: Principles of Administration

    • CHEMOTHERAPY ADMINISTRATION
    • DRUG ADMINISTRATION
    • VASCULAR ACCESS DEVICES
    • CONCLUSION
    • REFERENCES
    • APPENDIX 16A Oral Chemotherapy and Hormonal Agents
    • APPENDIX 16B Intravenous Chemotherapy Agents

    Chemotherapy Toxicities and Management

    • INTRODUCTION
    • PRETREATMENT EVALUATION: RISK ANALYSIS
    • QUALITY OF LIFE AND CHEMOTHERAPY TOXICITY
    • SELF-CARE
    • PATIENT EDUCATION AND FOLLOW-UP
    • CHEMOTHERAPY TOXICITIES
    • CONCLUSION
    • REFERENCES

    Principles and Techniques of Blood and Marrow Transplantation

    • HISTORICAL DEVELOPMENTS
    • HEMATOPOIESIS AND TRANSPLANT IMMUNOLOGY
    • TYPES OF TRANSPLANT
    • SOURCES OF STEM CELLS
    • INDICATIONS FOR TRANSPLANT AND SURVIVAL OUTCOMES (DISEASES TREATED)
    • PATIENT EVALUATION
    • COMMON PREPARATIVE REGIMENS
    • TRANSPLANT COURSE
    • SITE OF CARE DELIVERY
    • OUTPATIENT FOLLOW-UP
    • FUTURE DIRECTIONS
    • REFERENCES

    Complications of Hematopoietic Cell Transplantation

    • INTRODUCTION
    • PROPHYLACTIC SUPPORT
    • PERITRANSPLANT SUPPORTIVE CARE
    • EVALUATION AND TREATMENT OF COMPLICATIONS
    • ACUTE COMPLICATIONS
    • LATE COMPLICATIONS
    • CONCLUSION
    • REFERENCES

    Biotherapy

    • INTRODUCTION
    • HISTORICAL PERSPECTIVE
    • IMMUNOLOGY OVERVIEW
    • INTERLEUKIN 2
    • THE INTERFERONS
    • BACILLUS CALMETTE-GUÉRIN
    • IMIQUIMOD
    • CANCER VACCINES
    • ADOPTIVE CELLULAR TRANSFER THERAPY
    • CONCLUSION
    • REFERENCES

    Targeted Therapy

    • INTRODUCTION
    • SIGNAL TRANSDUCTION
    • RECEPTOR KINASE PATHWAYS
    • INTRACELLULAR SIGNALING KINASE PATHWAYS
    • ANGIOGENESIS PATHWAYS
    • MONOCLONAL ANTIBODIES
    • TYROSINE KINASE INHIBITORS
    • NURSING MANAGEMENT
    • FUTURE IMPLICATIONS
    • REFERENCES

    Gene Therapy

    • INTRODUCTION
    • GENETIC DISORDERS
    • PRINCIPLES AND GOALS OF GENE THERAPY
    • VECTORS FOR GENE TRANSFER
    • FUTURE APPROACHES TO GENE THERAPY
    • CLINICAL PROTOCOLS FOR GENE THERAPY
    • ETHICAL, SOCIAL, AND LEGAL ISSUES IN GENE THERAPY
    • PRACTICE IMPLICATIONS FOR ONCOLOGY NURSES
    • CONCLUSION
    • REFERENCES

    Hematopoietic Therapy

    • INTRODUCTION
    • HEMATOPOIETIC GROWTH FACTORS
    • TRANSFUSION THERAPY
    • CONCLUSION
    • REFERENCES

    Complementary and Alternative Medicine (CAM) Therapies in Integrative Oncology

    • INTRODUCTION
    • CAM REGULATION
    • EVIDENCE-BASED PRACTICE
    • INTEGRATIVE ONCOLOGY: EFFICACY AND SAFETY OF COMMONLY USED MODALITIES
    • SYMPTOM MANAGEMENT
    • EDUCATION
    • FUTURE TRENDS
    • REFERENCES

PART IV Cancer Symptom Management

    Evidence-Based Oncology Nursing

    • INTRODUCTION
    • EVIDENCE-BASED NURSING
    • A FRAMEWORK: IMPLEMENTATION OF EVIDENCE-BASED PRACTICE
    • BECOMING A NURSE WHO BASES CARE UPON EVIDENCE
    • CONCLUSION
    • REFERENCES

    Cancer-Related Distress

    • INTRODUCTION
    • HISTORICAL PERSPECTIVE
    • LANGUAGE
    • INCIDENCE OF DISTRESS ASSOCIATED WITH CANCER
    • ETIOLOGY OF RISK FACTORS FOR DISTRESS
    • BARRIERS TO IDENTIFICATION AND TREATMENT
    • SPECIAL POPULATIONS
    • CLINICAL MANIFESTATIONS OF DISTRESS
    • ASSESSMENT OF DISTRESS
    • THERAPEUTIC APPROACHES AND NURSING CARE
    • CONCLUSION
    • REFERENCES

    Cancer Pain Management

    • SCOPE OF THE PROBLEM
    • EPIDEMIOLOGY OF CANCER PAIN
    • ETIOLOGY OF CANCER PAIN
    • PHYSIOLOGICAL ALTERATIONS
    • TYPES OF PAIN
    • CLINICAL MANIFESTATIONS
    • ASSESSMENT
    • PHARMACOLOGICAL MANAGEMENT OF PAIN
    • INTERVENTIONAL MANAGEMENT OF PAIN
    • NONPHARMACOLOGICAL MANAGEMENT OF PAIN
    • CONCLUSION
    • REFERENCES

    Infection

    • SCOPE OF THE PROBLEM
    • PHYSIOLOGICAL ALTERATIONS
    • CLINICAL MANIFESTATIONS
    • ASSESSMENT AND GRADING
    • THERAPEUTIC APPROACHES AND NURSING CARE
    • CONCLUSION
    • REFERENCES

    Bleeding

    • SCOPE OF THE PROBLEM
    • PHYSIOLOGY OF BLEEDING
    • PATHOPHYSIOLOGY OF BLEEDING
    • ASSESSMENT FOR BLEEDING
    • THERAPEUTIC APPROACHES AND NURSING CARE
    • CONCLUSION
    • REFERENCES

    Cancer-Related Fatigue

    • SCOPE OF THE PROBLEM
    • PSYCHOPHYSIOLOGICAL MODELS OF CRF
    • EVALUATION OF THE PATIENT WITH CANCER-RELATED FATIGUE
    • INTERVENTIONS FOR FATIGUE
    • CONCLUSION AND FUTURE DIRECTIONS
    • REFERENCES

    Hypersensitivity Reactions to Antineoplastic Drugs

    • SCOPE OF THE PROBLEM
    • PHYSIOLOGICAL ALTERATIONS
    • CLINICAL MANIFESTATIONS
    • THERAPEUTIC APPROACHES AND NURSING CARE
    • CONCLUSION
    • REFERENCES

    Oral Mucositis

    • SCOPE OF THE PROBLEM
    • PHYSIOLOGICAL ALTERATIONS
    • CLINICAL MANIFESTATIONS
    • ASSESSMENT AND GRADING
    • THERAPEUTIC APPROACHES AND NURSING CARE
    • CONCLUSION
    • REFERENCES

    Nutritional Disturbances

    • SCOPE OF THE PROBLEM
    • NORMAL NUTRITIONAL PHYSIOLOGY
    • PATHOPHYSIOLOGY
    • CLINICAL MANIFESTATIONS
    • SCREENING, ASSESSMENT, AND GRADING
    • THERAPEUTIC APPROACHES AND NURSING CARE
    • CONCLUSION
    • REFERENCES

    Paraneoplastic Syndromes

    • INTRODUCTION
    • NEUROLOGICAL PARANEOPLASTIC SYNDROMES
    • ENDOCRINE PARANEOPLASTIC SYNDROMES
    • HEMATOLOGIC PARANEOPLASTIC SYNDROMES
    • RENAL PARANEOPLASTIC SYNDROMES
    • MISCELLANEOUS PARANEOPLASTIC SYNDROMES
    • CONCLUSION
    • REFERENCES

    Malignant Effusions

    • INTRODUCTION
    • PLEURAL EFFUSIONS
    • PERICARDIAL EFFUSIONS
    • MALIGNANT PERITONEAL EFFUSIONS
    • CONCLUSION
    • REFERENCES

    Sexual and Reproductive Dysfunction

    • SCOPE OF THE PROBLEM
    • PHYSIOLOGICAL ALTERATIONS
    • CLINICAL MANIFESTATIONS: EFFECT OF CANCER THERAPY ON GONADAL FUNCTION
    • ASSESSMENT
    • THERAPEUTIC APPROACHES AND NURSING CARE
    • PREGNANCY AND CANCER
    • CONCLUSION
    • REFERENCES

PART V Oncologic Emergencies

    Cardiac Tamponade

    • SCOPE OF THE PROBLEM
    • DEFINITIONS
    • PHYSIOLOGICAL ALTERATIONS
    • CLINICAL MANIFESTATIONS
    • ASSESSMENT
    • THERAPEUTIC APPROACHES AND NURSING CARE
    • CONCLUSION
    • REFERENCES

    Disseminated Intravascular Coagulation

    • SCOPE OF THE PROBLEM
    • PHYSIOLOGICAL ALTERATIONS
    • CLINICAL MANIFESTATIONS
    • ASSESSMENT
    • THERAPEUTIC APPROACHES AND NURSING CARE
    • CONCLUSION
    • REFERENCES

    Hypercalcemia of Malignancy

    • SCOPE OF THE PROBLEM
    • CLINICAL MANIFESTATIONS OF HYPERCALCEMIA
    • ASSESSMENT
    • GRADING HYPERCALCEMIA IN MALIGNANT DISEASE
    • THERAPEUTIC APPROACHES
    • NURSING MANAGEMENT
    • CONCLUSION
    • REFERENCES

    Septic Shock

    • SCOPE OF THE PROBLEM
    • PHYSIOLOGICAL ALTERATIONS
    • CLINICAL MANIFESTATIONS
    • ASSESSMENT AND GRADING
    • THERAPEUTIC APPROACHES AND NURSING CARE
    • CONCLUSION
    • REFERENCES

    Spinal Cord Compression

    • SCOPE OF THE PROBLEM
    • PATHOPHYSIOLOGY
    • CLINICAL MANIFESTATIONS AND PHYSICAL ASSESSMENT
    • DIAGNOSTIC EVALUATION
    • THERAPEUTIC APPROACHES AND NURSING CARE
    • CONCLUSION
    • REFERENCES

    Superior Vena Cava Syndrome

    • SCOPE OF THE PROBLEM
    • PHYSIOLOGICAL ALTERATIONS
    • CLINICAL MANIFESTATIONS
    • THERAPEUTIC APPROACHES AND NURSING CARE
    • CONCLUSION
    • REFERENCES

    Syndrome of Inappropriate Antidiuretic Hormone

    • SCOPE OF THE PROBLEM
    • ETIOLOGY AND RISK FACTORS
    • PHYSIOLOGICAL ALTERATIONS
    • CLINICAL MANIFESTATIONS
    • ASSESSMENT AND GRADING
    • THERAPEUTIC APPROACHES AND NURSING CARE
    • CONCLUSION
    • REFERENCES

    Tumor Lysis Syndrome

    • SCOPE OF THE PROBLEM
    • CLASSIFICATION AND GRADING
    • PHYSIOLOGICAL ALTERATIONS
    • CLINICAL MANIFESTATIONS
    • THERAPEUTIC APPROACHES AND NURSING CARE
    • CONCLUSION
    • REFERENCES

PART VI The Care of Individuals with Specific Cancers

    AIDS-Related Malignancies

    • INTRODUCTION
    • HIV DISEASE AND CANCER
    • NON-HODGKIN’S LYMPHOMA
    • PRIMARY CENTRAL NERVOUS SYSTEM LYMPHOMA
    • KAPOSI SARCOMA
    • CERVICAL CANCER
    • NON-AIDS-DEFINING MALIGNANCIES
    • CLINICAL TRIALS AND HIV
    • CONCLUSION
    • REFERENCES

    Bone and Soft Tissue Sarcomas

    • INTRODUCTION
    • EPIDEMIOLOGY
    • ETIOLOGY
    • SCREENING AND EARLY DETECTION
    • PATHOPHYSIOLOGY
    • CLINICAL MANIFESTATIONS
    • ASSESSMENT
    • PROGNOSTIC INDICATORS
    • CLASSIFICATION AND STAGING
    • THERAPEUTIC APPROACHES AND NURSING CARE
    • SURGERY
    • RADIOTHERAPY
    • CHEMOTHERAPY
    • TARGETED THERAPY
    • DESCRIPTION OF SELECTED SARCOMAS
    • SYMPTOM MANAGEMENT AND SUPPORTIVE CARE
    • FUTURE TRENDS
    • REFERENCES

    Bladder Cancer

    • INTRODUCTION
    • EPIDEMIOLOGY
    • ETIOLOGY
    • PREVENTION, SCREENING, AND EARLY DETECTION
    • PATHOPHYSIOLOGY
    • CLINICAL MANIFESTATIONS
    • ASSESSMENT
    • CLASSIFICATION AND STAGING
    • THERAPEUTIC APPROACHES AND NURSING CARE
    • SYMPTOM MANAGEMENT AND SUPPORTIVE CARE
    • CONCLUSION
    • REFERENCES

    Breast Cancer

    • INTRODUCTION
    • EPIDEMIOLOGY
    • ETIOLOGY
    • PREVENTION, SCREENING, AND EARLY DETECTION
    • GENETIC COUNSELING PROGRAMS
    • PATHOPHYSIOLOGY
    • ASSESSMENT
    • CLASSIFICATION AND STAGING
    • THERAPEUTIC APPROACHES AND NURSING CARE
    • METASTATIC BREAST CANCER
    • BREAST CANCER IN SPECIAL POPULATIONS
    • SYMPTOM MANAGEMENT AND SUPPORTIVE CARE
    • FUTURE TRENDS
    • CONCLUSION
    • REFERENCES

    Central Nervous System Cancers

    • INTRODUCTION
    • BRAIN TUMORS
    • SPINAL CORD TUMORS
    • REFERENCES

    Cervical Cancer

    • INTRODUCTION
    • EPIDEMIOLOGY
    • ETIOLOGY
    • PREVENTION, SCREENING, AND EARLY DETECTION
    • PREINVASIVE DISEASE
    • INVASIVE DISEASE
    • CLASSIFICATION AND STAGING
    • THERAPEUTIC APPROACHES AND NURSING CARE
    • SYMPTOM MANAGEMENT AND SUPPORTIVE CARE
    • CONCLUSION
    • REFERENCES

    Colon, Rectal, and Anal Cancers

    • COLON CANCER
    • RECTAL CANCER
    • ANAL CANCER
    • REFERENCES

    Endocrine Malignancies

    • INTRODUCTION
    • THYROID TUMORS
    • PARATHYROID TUMORS
    • PITUITARY TUMORS
    • ADRENAL TUMORS
    • MULTIPLE ENDOCRINE NEOPLASIA
    • CONCLUSION
    • REFERENCES

    Endometrial Cancer

    • INTRODUCTION
    • EPIDEMIOLOGY
    • ETIOLOGY
    • PREVENTION, SCREENING, AND EARLY DETECTION
    • PATHOPHYSIOLOGY
    • CLINICAL MANIFESTATIONS
    • ASSESSMENT
    • CLASSIFICATION AND STAGING
    • THERAPEUTIC APPROACHES AND NURSING CARE
    • SYMPTOM MANAGEMENT AND SUPPORTIVE CARE
    • CONCLUSION
    • REFERENCES

    Esophageal Cancer

    • INTRODUCTION
    • EPIDEMIOLOGY
    • ETIOLOGY
    • PREVENTION, SCREENING, AND EARLY DETECTION
    • PATHOPHYSIOLOGY
    • CLINICAL MANIFESTATIONS
    • ASSESSMENT
    • CLASSIFICATION AND STAGING
    • THERAPEUTIC APPROACHES AND NURSING CARE
    • SYMPTOM MANAGEMENT AND SUPPORTIVE CARE
    • CONCLUSION
    • REFERENCES

    Gallbladder and Bile Duct Cancer

    • GALLBLADDER CANCER
    • BILE DUCT CANCER
    • CONCLUSION
    • REFERENCES

    Head and Neck Malignancies

    • INTRODUCTION
    • EPIDEMIOLOGY
    • ANATOMY
    • ETIOLOGY AND RISK FACTORS
    • CLINICAL MANIFESTATIONS
    • PATHOPHYSIOLOGY
    • ASSESSMENT
    • IMAGING
    • CLASSIFICATION AND STAGING
    • THERAPEUTIC APPROACHES
    • FUTURE TREATMENT AND MANAGEMENT STRATEGIES
    • HEAD AND NECK SPECIALIZED PROGRAMS OF RESEARCH EXCELLENCE
    • TREATMENT STRATEGIES FOR SPECIFIC HEAD AND NECK CANCERS
    • SYMPTOM MANAGEMENT AND SUPPORTIVE CARE
    • MULTIDISCIPLINARY CARE
    • REFERENCES

    Leukemia and Myelodysplastic Syndromes

    • INTRODUCTION
    • EPIDEMIOLOGY
    • ETIOLOGY
    • PREVENTION, SCREENING, AND EARLY DETECTION
    • PATHOBIOLOGY
    • CLASSIFICATION AND STAGING
    • CLINICAL MANIFESTATIONS
    • ASSESSMENT
    • THERAPEUTIC APPROACHES AND NURSING MANAGEMENT
    • SYMPTOM MANAGEMENT AND SUPPORTIVE CARE
    • CONCLUSION
    • REFERENCES

    Liver Cancer

    • INTRODUCTION
    • EPIDEMIOLOGY
    • ETIOLOGY
    • PREVENTION, SCREENING, AND EARLY DETECTION
    • PATHOPHYSIOLOGY
    • CLINICAL MANIFESTATIONS
    • ASSESSMENT
    • CLASSIFICATION AND STAGING
    • THERAPEUTIC APPROACHES AND NURSING CARE
    • SYMPTOM MANAGEMENT AND SUPPORTIVE CARE
    • CONCLUSION
    • REFERENCES

    Lung Cancer

    • INTRODUCTION
    • EPIDEMIOLOGY
    • ETIOLOGY
    • PREVENTION
    • SCREENING AND EARLY DETECTION
    • PATHOPHYSIOLOGY
    • CLINICAL MANIFESTATIONS
    • ASSESSMENT
    • CLASSIFICATION AND STAGING
    • THERAPEUTIC APPROACHES AND NURSING CARE
    • SYMPTOM MANAGEMENT AND SUPPORTIVE CARE
    • CONCLUSION
    • REFERENCES

    Lymphomas

    • INTRODUCTION
    • LYMPHOID TISSUES AND THE IMMUNE SYSTEM
    • DIAGNOSIS
    • HODGKIN’S DISEASE
    • NON-HODGKIN’S LYMPHOMA
    • CONCLUSION
    • REFERENCES

    Multiple Myeloma

    • INTRODUCTION
    • EPIDEMIOLOGY
    • ETIOLOGY
    • RISK FACTORS
    • PREVENTION, SCREENING, AND EARLY DETECTION
    • PATHOPHYSIOLOGY
    • CLINICAL MANIFESTATIONS
    • ASSESSMENT
    • CLASSIFICATION AND STAGING
    • THERAPEUTIC APPROACHES AND NURSING CARE
    • SYMPTOM MANAGEMENT AND NURSING CARE
    • CONCLUSION
    • REFERENCES

    Ovarian Cancer

    • INTRODUCTION
    • EPIDEMIOLOGY
    • ETIOLOGY
    • PREVENTION, SCREENING, AND EARLY DETECTION
    • PATHOPHYSIOLOGY
    • CLINICAL MANIFESTATIONS
    • ASSESSMENT
    • CLASSIFICATION AND STAGING
    • THERAPEUTIC APPROACHES AND NURSING CARE
    • SYMPTOM MANAGEMENT AND SUPPORTIVE CARE
    • CONTINUITY OF CARE
    • FUTURE TRENDS
    • REFERENCES

    Pancreatic Cancer

    • INTRODUCTION
    • EPIDEMIOLOGY
    • PREVENTION, SCREENING, AND EARLY DETECTION
    • PATHOPHYSIOLOGY
    • CLINICAL MANIFESTATIONS
    • ASSESSMENT
    • CLASSIFICATION AND STAGING
    • THERAPEUTIC APPROACHES AND NURSING CARE
    • SYMPTOM MANAGEMENT AND NURSING CARE
    • FUTURE TRENDS
    • REFERENCES

    Prostate Cancer

    • EPIDEMIOLOGY
    • ETIOLOGY
    • PREVENTION, SCREENING, AND EARLY DETECTION
    • PATHOPHYSIOLOGY
    • CLINICAL MANIFESTATIONS
    • ASSESSMENT
    • CLASSIFICATION AND STAGING
    • THERAPEUTIC APPROACHES AND NURSING CARE
    • SYMPTOM MANAGEMENT AND SUPPORTIVE CARE
    • CONCLUSION
    • REFERENCES

    Renal Cancer

    • INTRODUCTION
    • EPIDEMIOLOGY
    • ETIOLOGY
    • PREVENTION, SCREENING, AND EARLY DETECTION
    • PATHOPHYSIOLOGY
    • CLINICAL MANIFESTATIONS
    • ASSESSMENT
    • CLASSIFICATION AND STAGING
    • THERAPEUTIC APPROACHES AND NURSING CARE
    • CONCLUSION
    • REFERENCES

    Skin Cancer

    • INTRODUCTION
    • EPIDEMIOLOGY
    • ETIOLOGY
    • CALCULATING MELANOMA RISK
    • PREVENTION
    • PATHOPHYSIOLOGY
    • CLINICAL MANIFESTATIONS
    • ASSESSMENT
    • CLASSIFICATION AND STAGING
    • THERAPEUTIC APPROACHES AND NURSING CARE
    • CONCLUSION
    • REFERENCES

    Stomach Cancer

    • INTRODUCTION
    • EPIDEMIOLOGY
    • ETIOLOGY
    • PREVENTION, SCREENING, AND EARLY DETECTION
    • PATHOPHYSIOLOGY
    • CLINICAL MANIFESTATIONS
    • ASSESSMENT
    • CLASSIFICATION AND STAGING
    • THERAPEUTIC APPROACHES AND NURSING CARE
    • SYMPTOM MANAGEMENT AND SUPPORTIVE CARE
    • CONCLUSION
    • REFERENCES

    Testicular Germ Cell Cancer

    • INTRODUCTION
    • EPIDEMIOLOGY
    • ETIOLOGY
    • PREVENTION, SCREENING, AND EARLY DETECTION
    • PATHOPHYSIOLOGY
    • CLINICAL MANIFESTATIONS
    • ASSESSMENT
    • CLASSIFICATION AND STAGING
    • THERAPEUTIC APPROACHES AND NURSING CARE
    • SYMPTOM MANAGEMENT AND SUPPORTIVE CARE
    • CONCLUSION
    • REFERENCES

    Vulvar and Vaginal Cancer

    • INTRODUCTION
    • VULVAR CANCER
    • VAGINAL CANCER
    • CONCLUSION
    • REFERENCES

PART VII Dimensions of Cancer Survivorship

    Cancer Survivorship: A Critical Aspect of Care

    • INTRODUCTION
    • OVERVIEW OF CANCER SURVIVORSHIP
    • LATE EFFECTS IN CANCER SURVIVORS
    • PSYCHOSOCIAL LATE EFFECTS IN CANCER SURVIVORS
    • SPECIAL POPULATIONS OF CANCER SURVIVORS
    • CANCER SURVIVORSHIP CARE PLANNING
    • HEALTH PROMOTION AMONG CANCER SURVIVORS
    • SOCIAL ISSUES
    • ADVOCACY
    • CANCER SURVIVORSHIP RESEARCH
    • CONCLUSION
    • REFERENCES

    Late Effects of Cancer Treatment

    • INTRODUCTION
    • OVERVIEW OF LATE EFFECTS FOLLOWING CANCER TREATMENT
    • LATE EFFECTS IN SPECIFIC POPULATIONS OF CANCER SURVIVORS
    • PROVIDING CLINICAL CARE FOR CANCER SURVIVORS
    • THE SURVIVORSHIP CARE PLAN
    • RESOURCES
    • CONCLUSION
    • REFERENCES

    Family and Caregiver Issues

    • INTRODUCTION
    • WHY HELP FAMILIES OF PATIENTS WITH CANCER?
    • BARRIERS TO HELPING FAMILIES OF PATIENTS WITH CANCER
    • A THEORETICAL PERSPECTIVE
    • EFFECT OF CANCER ON THE QUALITY OF LIFE OF FAMILY MEMBERS
    • PRACTICAL STRATEGIES FOR HELPING PATIENTS AND FAMILY MEMBERS
    • CONCLUSION
    • REFERENCES

    Spiritual Responses to Cancer

    • INTRODUCTION
    • DEFINITIONS
    • WHY ADDRESS SPIRITUALITY?
    • SPIRITUALITY THROUGHOUT THE CANCER EXPERIENCE
    • CAREGIVER PERSPECTIVES
    • PROVIDING SPIRITUAL CARE
    • CONCLUSION
    • REFERENCES

PART VIII Palliative Care and End of Life

    Principles and Issues in Palliative Care

    • INTRODUCTION
    • HISTORICAL PERSPECTIVES
    • MODELS OF PALLIATIVE CARE
    • BARRIERS TO PROVIDING QUALITY PALLIATIVE CARE
    • LACK OF EVIDENCED-BASED INTERVENTIONS
    • ETHICAL AND LEGAL ISSUES IN PALLIATIVE CARE
    • CHALLENGES FOR THE FUTURE OF PALLIATIVE CARE
    • CONCLUSION
    • REFERENCES

    Care During the Final Days of Life

    • INTRODUCTION
    • SYMPTOMS DURING THE FINAL DAYS OF LIFE
    • DIFFICULT SITUATIONS
    • PATIENT AND FAMILY EDUCATION
    • CONCLUSION
    • REFERENCES

PART IX Professional Issues for the Cancer Nurse

    The Advanced Oncology Practice Nurse

    • INTRODUCTION
    • ADVANCED PRACTICE NURSING DEFINED
    • ADVANCED PRACTICE IN ONCOLOGY SPECIALTY
    • ONCOLOGY ADVANCED PRACTICE NURSING EDUCATION
    • REGULATION OF ADVANCED ONCOLOGY NURSING PRACTICE
    • ECONOMICS AND ADVANCED ONCOLOGY PRACTICE
    • IMPLEMENTING ADVANCED ONCOLOGY NURSING PRACTICE: WORKING COLLABORATIVELY
    • CHALLENGES FOR THE FUTURE
    • CONCLUSION
    • REFERENCES
    • APPENDIX A: ONCOLOGY CLINICAL NURSE SPECIALIST PRACTICE COMPETENCIES
    • NURSE AND NURSING PRACTICE SPHERE OF INFLUENCE
    • ORGANIZATION/SYSTEMS SPHERE
    • APPENDIX B: ONCOLOGY NURSE PRACTITIONER COMPETENCIES
    • NURSE PRACTITIONER–PATIENT RELATIONSHIP
    • TEACHING/COACHING FUNCTION
    • PROFESSIONAL ROLE
    • NEGOTIATING HEALTH CARE DELIVERY SYSTEMS
    • MONITORING AND ENSURING THE QUALITY OF HEALTH CARE PRACTICE
    • CARING FOR DIVERSE POPULATIONS

    Legal Issues

    • INTRODUCTION
    • PATIENT SAFETY
    • CHEMOTHERAPY MEDICATION ERRORS
    • HYPERSENSITIVITY AND INFUSION-RELATED REACTIONS
    • VESICANT EXTRAVASATION
    • RESPONDING TO ERRORS AND ADVERSE EVENTS
    • RISK MANAGEMENT
    • COMPLAINTS AND LITIGATION
    • PRIVACY PROTECTION
    • TELEPHONE AND ELECTRONIC COMMUNICATION
    • PAIN MANAGEMENT
    • CONCLUSION
    • REFERENCES

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