FITZPATRICK'S DERMATOLOGY IN GENERAL MEDICINE
Author: Klaus Wolff, MD, FRCP, Lowell Goldsmith, MD, Stephen Katz, MD, PHD, Barbara Gilchrest, MD, Amy Paller, MD, David Leffell, MD
Publisher: McGraw-Hill
Publication Date: 2008
Publisher: McGraw-Hill
Publication Date: 2008
ISBN 10: 0071466908
ISBN 13: 9780071466905
Edition: 7th
ISBN 13: 9780071466905
Edition: 7th
Description:
The must-have reference in dermatology-now completely revised and updated! In no other source but Fitzpatrick's can you find the most comprehensive, current, and authoritative coverage of the entire spectrum of dermatologic science, diagnosis, treatment, and management. Now in a more accessible format, with everything you need to know about skin, skin symptoms, and skin diseases right at your fingertips-from the basic science of the skin as an immunoprotective organ -- to the day-to-day clinical issues of managing skin diseases like psoriasis, acne, and skin cancer. Encyclopedic in scope, yet skillfully edited so it's easy to read and use every day, this unsurpassed resource delivers a timely look at dermatologic therapeutics as well as dermatologic surgery and cosmetic dermatology. In addition, 3,000 eye-catching full-color photographs and hundreds of time-saving tables encapsulate core concepts, while scores of references facilitate further research.
Table of Contents
Front Matter
The Epidemiology and Burden of Skin Disease
Evidence-Based Dermatology
Public Health in Dermatology
Structure of Skin Lesions and Fundamentals of Clinical Diagnosis
Diagnostic Procedures and Devices
Basic Pathologic Reactions of the Skin
Development and Structure of Skin
Genetics in Relation to the Skin
- The Human Genome in Dermatology
- The Human Genome
- Genetic and Genomic Databases
- Chromosome and Gene Structure
- Gene Expression
- Finding Disease Genes
- Gene Mutations and Polymorphisms
- Mendelian Disorders
- Chromosomal Disorders
- Mitochondrial Disorders
- Complex Trait Genetics
- Mosaicism
- Epigenetics
- Histocompatibility Antigen Disease Association
- Genetic Counseling
- Prenatal Diagnosis
- Gene Therapy
- References
Basic Science Approaches to the Pathophysiology of Skin Disease
Innate and Adaptive Immunity in the Skin
Cytokines
- The Concept of Cytokines
- Classifications of Cytokines
- Signal Transduction Pathways Shared by Cytokines
- Interleukin 1 Family of Cytokines (Interleukins 1α, 1β, 18, 33)
- Tumor Necrosis Factor: The Other Primary Cytokine
- Ligands of the Class I (Hematopoietin Receptor) Family of Cytokine Receptors
- Ligands of the Class II Family of Cytokine Receptors
- Transforming Growth Factor-β Family and Its Receptors
- Chemokines: Secondary Cytokines Central to Leukocyte Mobilization
- Cytokine Network—Therapeutic Implications and Applications
- References
Chemokines
Allergic Contact Dermatitis
Atopic Dermatitis (Atopic Eczema)
Nummular Eczema and Lichen Simplex Chronicus/Prurigo Nodularis
Vesicular Palmoplantar Eczema
Autosensitization Dermatitis
Psoriasis
Psoriatic Arthritis
Reactive Arthritis
Pustular Eruptions of Palms and Soles
Seborrheic Dermatitis
- Seborrheic Dermatitis: Introduction
- Epidemiology
- Etiology and Pathogenesis
- Seborrhea
- Microbial Effects
- Miscellaneous
- Immunodeficiency and Seborrheic Dermatitis
- Psoriasis and Seborrheic Dermatitis
- Clinical Findings
- Seborrheic Dermatitis in Infants
- Erythroderma Desquamativum (Leiner’s Disease)
- Seborrheic Dermatitis in Adults
- Pityriasis amiantacea
- Seborrheic Dermatitis in Human Immunodeficiency Virus–Infected Individuals
- Histopathology
- Treatment
- References
Exfoliative Dermatitis
Pityriasis Rubra Pilaris
Parapsoriasis and Pityriasis Lichenoides
Lichen Planus
Lichen Nitidus
Graft-Versus-Host Disease
Skin Disease in Acute and Chronic Immunosuppression
Regulation of the Production and Activation of Neutrophils and Eosinophils
Acute Febrile Neutrophilic Dermatosis (Sweet Syndrome)
Pyoderma Gangrenosum
Granuloma Faciale
Sub-Corneal Pustular Dermatosis (Sneddon-Wilkinson Disease)
Eosinophils in Cutaneous Diseases
Humoral Immunity and Complement
- Humoral Immunity and Complement: Introduction
- Antibody Structure
- Antibody Classes
- Mechanisms for the Generation of Antibody Diversity
- B-Cell Maturation
- Antigens Bound by B Cells
- B-Cell Activation and Antibody Function
- B Cells and Antibodies in Disease
- Complement System
- Pathways of Complement Activation
- Functions of Complement Proteins
- Complement Receptors
- Regulation of Complement Activation
- Complement and Disease
- References
Urticaria and Angioedema
Erythema Multiforme
Epidermal Necrolysis (Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis)
Cutaneous Reactions to Drugs
Pityriasis Rosea
Erythema Annulare Centrifugum and Other Figurate Erythemas
Granuloma Annulare
Epidermal Growth and Differentiation
Skin as an Organ of Protection
- Skin as an Organ of Protection: Introduction
- Structure of the Stratum Corneum: Physical Permeability Barrier
- Epidermal Proliferation and Differentiation in Skin Barrier Function
- Experimental Barrier Disruption and Gene Modification in Epidermal Differentiation
- Functions of the Sub-Corneal Epidermal Layers
- Pathologic Skin Barriers: Skin Barrier Function in Dermatoses
- Treatment Implications and Approaches: Restoring the Skin’s Protective Function
- References
Irritant Contact Dermatitis
The Ichthyoses
- The Ichthyoses: Introduction
- Clinical Presentation
- Etiology and Pathogenesis
- Ichthyosis Vulgaris
- X-Linked Recessive Ichthyosis
- Autosomal Recessive Congenital Ichthyosis
- Lamellar Ichthyosis
- Congenital Ichthyosiform Erythroderma
- Epidermolytic Hyperkeratosis
- Disorders Resembling Epidermolytic Hyperkeratosis
- Ichthyosis in the Newborn
- Less-Common Ichthyoses
- Acquired Ichthyosis
- Treatment
- Prenatal Diagnosis
- References
Inherited Keratodermas of Palms and Soles
Acantholytic Disorders of the Skin: Darier-White Disease, Acrokeratosis Verruciformis, Grover Disease, and Hailey-Hailey Disease
Porokeratosis
Epidermal and Epidermal-Dermal Cohesion
Pemphigus
Paraneoplastic Pemphigus
Bullous Pemphigoid
Cicatricial Pemphigoid
Linear Immunoglobulin A Dermatosis and Chronic Bullous Disease of Childhood
Pemphigoid Gestationis (Herpes Gestationis)
Epidermolysis Bullosa Acquisita
Dermatitis Herpetiformis
Inherited Epidermolysis Bullosa
Collagen, Elastic Fibers, and Extracellular Matrix of the Dermis
Morphea
Lichen Sclerosus
Dermal Hypertrophies
Anetoderma and Other Atrophic Disorders of the Skin
Constricting Bands (Ainhum and Pseudoainhum)
Acquired Perforating Disorders
Panniculitis
- Panniculitis: Introduction
- Histology of Subcutaneous Fat
- Classification of Panniculitides
- Mostly Septal Panniculitis with Vasculitis
- Mostly Septal Panniculitis Without Vasculitis
- Mostly Lobular Panniculitis with Vasculitis
- Mostly Lobular Panniculitis Without Vasculitis
- Disorders Erroneously Considered as Specific Variants of Panniculitis
- References
Lipodystrophy
Biology of Melanocytes
Albinism and Other Genetic Disorders of Pigmentation
- Epidemiology
- Etiology, Pathogenesis, and Clinical Features
- Differential Diagnosis of Albinism and Congenital Disorders of Pigmentation
- Complications of Albinism and Congenital Disorders of Pigmentation
- Prognosis and Clinical Course of Albinism and Congenital Disorders of Pigmentation
- Treatment
- Prevention of Albinism and Congenital Disorders of Pigmentation
- References
Vitiligo
Hypomelanoses and Hypermelanoses
Biology and Pathology of the Oral Cavity
Diseases and Disorders of the Male Genitalia
Diseases and Disorders of the Female Genitalia
- Diseases and Disorders of the Female Genitalia: Introduction
- Epidemiology
- Etiology and Pathogenesis
- Clinical Findings
- Laboratory Tests
- Differential Diagnosis
- Prognosis and Clinical Course
- Treatment
- Common Normal Variants
- Inflammatory Dermatoses
- Bullous and Erosive Diseases
- Ulcers
- Abscesses
- Vulvodynia
- Pruritus Vulvae
- References
Biology of Sebaceous Glands
Acne Vulgaris and Acneiform Eruptions
Rosacea
Perioral Dermatitis
Biology of Eccrine, Apocrine, and Apoeccrine Sweat Glands
Disorders of the Eccrine Sweat Glands and Sweating
- Disorders of the Eccrine Sweat Glands and Sweating: Introduction
- In Vivo Methods of Studying Sweat Gland Function
- Visual Examination of the Skin
- Disorders of Sweating
- Primary Focal (Essential) Hyperhidrosis
- Secondary Causes of Localized Hyperhidrosis
- Secondary Causes of Generalized Hyperhidrosis
- Disorders Causing Hypohidrosis and Anhidrosis
- Secondary Anhidrosis Associated with Neurologic Disorders
- Anhidrosis Associated with Other Disorders of Skin and Sweat Glands
- References
Disorders of the Apocrine Sweat Glands
Biology of Hair Follicles
Keratosis Pilaris and Other Inflammatory Follicular Keratotic Syndromes
Hair Growth Disorders
- Hair Growth Disorders: Introduction
- Principles of Hair Follicle Pathobiology
- Diagnostic Techniques
- Alopecia: Diffuse (Global) Hair Loss
- Hair Shaft Abnormalities
- Abnormalities of Hair Follicle Cycling
- Alopecia Areata
- Non-Scarring Hair Loss: Production Decline
- Traumatic Hair Loss
- Primary or Acquired Hair Shaft Abnormalities
- Cicatricial Alopecia (Destruction of the Follicle)
- Excess Hair
- References
Biology of Nails and Nail Disorders
- Biology of Nails
- Nail Signs as a Function of the Site of Pathology
- Hereditary and Congenital Nail Disorders
- Infectious Nail Disorders
- Environmental Nail Disorders
- Nail Tumors
- Nail Psoriasis
- Pustular Psoriasis
- Lichen Planus
- Parakeratosis Pustulosa
- Trachyonychia (Twenty-Nail Dystrophy)
- Darier’s Disease
- Alopecia Areata
- Atopic Dermatitis
- Yellow Nail Syndrome
- Nail Signs of Systemic Diseases
- Drug-Induced Nail Abnormalities
- Traumatic Nail Disorders
- References
Fundamentals of Cutaneous Photobiology and Photoimmunology
- Fundamentals of Cutaneous Photobiology and Photoimmunology: Introduction
- Ultraviolet and Visible Radiation
- Properties of Electromagnetic Radiation
- Sources of Ultraviolet and Visible Radiation
- Ultraviolet and Visible Radiation Dosimetry
- Optical Properties of Skin
- Absorption of Ultraviolet and Visible Radiation by Molecules in Skin
- Photochemical Reactions Leading to Skin Responses
- Photoimmunology
- References
Acute and Chronic Effects of Ultraviolet Radiation on the Skin
Abnormal Responses to Ultraviolet Radiation: Idiopathic, Probably Immunologic, and Photo-Exacerbated
Abnormal Responses to Ultraviolet Radiation: Photosensitivity Induced by Exogenous Agents
- Abnormal Responses to Ultraviolet Radiation: Photosensitivity Induced by Exogenous Agents: Introduction
- Incidence
- Phototoxicity
- Photoallergy
- Evaluation of Patients with Phototoxicity and Photoallergy
- Differential Diagnosis of Phototoxicity and Photoallergy
- Other Exogenous Agent–Induced Photodermatoses and Photo-Exacerbated Dermatoses
- References
Thermoregulation
Cold Injuries
- Cold Injuries: Introduction
- Physiologic Response to Cold
- Thermoregulation and Hunting Reaction
- Cold, Wind, Humidity, and Altitude
- Classification of Skin Cold Injuries
- Frostbite
- Nonfreezing Cold Injury and Dampness
- Winter Xerosis
- Acrocyanosis
- Erythrocyanosis
- Chilblains
- Cold Urticaria and Polymorphous Cold Eruption
- Cold Panniculitis and Related Entities
- Sclerema Neonatorum and Subcutaneous Fat Necrosis of the Newborn
- Erythromelalgia
- Raynaud Phenomenon
- Cryoglobulinemia
- Livedo Reticularis
- References
Thermal Injuries
Radiobiology and Radiation Effects
Skin Problems in Amputees and Ostomates
Corns and Calluses
Sports Dermatology
- Epidemiology
- Pyogenic Skin Infections
- Viral Skin Infections
- Fungal Infections
- Transmission of Blood-Borne Pathogens
- Heat and Cold Injury
- Skin Injuries
- Athlete’s Nodules
- Actinic Damage
- Allergic Contact Dermatitis
- Bites and Stings
- Skin Problems Related to Water Sports
- Histamine-Mediated Reactions
- Acneiform Lesions
- Dermatologic Problems of Special Athletes
- References
Decubitus (Pressure) Ulcers
Body Art
Neurobiology of the Skin
Pathophysiology and Clinical Aspects of Pruritus
Psychocutaneous Diseases
Cutaneous Manifestations of Drug Abuse
Skin Signs of Physical Abuse
Neonatal, Pediatric, and Adolescent Dermatology
Skin Changes and Diseases in Pregnancy
Aging of Skin
Genome Instability, DNA Repair, and Cancer
Carcinogenesis: Chemical
- Cutaneous Cancer and Public Health
- Chemicals Associated with Skin Cancer Induction in Humans
- The Nature of Chemical Carcinogens: Chemistry and Metabolism
- Hereditary Cancer Syndromes
- Animal Models Verify the Genetic Basis for Cutaneous Neoplasms
- Tumor Biology and Biochemistry
- Novel Molecular Targets Based on New Mechanistic Data
- References
Oncogenes, Tumor Suppressor Genes, and Viral Carcinogenesis
Carcinogenesis: Ultraviolet Radiation
- Ultraviolet Radiation as a Carcinogen
- Characteristics of Ultraviolet Radiation–Induced Cancers and Precancers
- Ultraviolet Radiation–Induced Genetic Alterations
- Ultraviolet Radiation–Induced Steps in Cancer and Cancer Prevention
- Animal Models of Skin Cancer: Clinical Implications
- Genetic Risk Factors for Ultraviolet Radiation Carcinogenesis
- Prevention
- Novel Therapeutic Approaches
- References
Epithelial Precancerous Lesions
- Epithelial Precancerous Lesions: Introduction
- Actinic Keratoses
- Arsenical Keratoses
- Thermal Keratoses
- Hydrocarbon Keratoses
- Chronic Radiation Keratoses
- Chronic Scar Keratoses
- Reactional Keratoses
- Puva Keratoses
- Viral Keratoses
- Squamous Cell Carcinoma In Situ (Bowen Disease)
- Erythroplasia of Queyrat
- Leukoplakia
- Erythroplakia (Erythroplasia)
- References
Squamous Cell Carcinoma
Basal Cell Carcinoma
Basal Cell Nevus Syndrome
Keratoacanthoma
Benign Epithelial Tumors, Hamartomas, and Hyperplasias
Appendage Tumors and Hamartomas of the Skin
Merkel Cell Carcinoma
Mammary and Extramammary Paget Disease
Benign Neoplasias and Hyperplasias of Melanocytes
Atypical Melanocytic Nevi
Cutaneous Melanoma
Malignant Fibrous Tumors of the Dermis
Vascular Tumors
Neoplasias and Hyperplasias of Muscular and Neural Origin
Kaposi Sarcoma
Neoplasms of Subcutaneous Fat
- Lipoma
- Lipomatosis
- Lipomatosis of Nerve (Fibrolipomatous Hamartoma of Nerve)
- Nevus Lipomatosus Superficialis
- Angiolipoma
- Spindle Cell Lipoma and Pleomorphic Lipoma
- Chondroid Lipoma
- Myolipoma of Soft Tissue
- Hibernoma
- Lipoblastoma/Lipoblastomatosis
- Hemosiderotic Fibrohistiocytic Lipomatous Lesion/Tumor
- Lipofibromatosis
- Atypical Lipomatous Tumor/Well-Differentiated Liposarcoma
- Dedifferentiated Liposarcoma
- Myxoid/Round Cell Liposarcoma
- Pleomorphic Liposarcoma
- References
Cutaneous Changes in Nutritional Disease
Cutaneous Changes in Errors of Amino Acid Metabolism
The Porphyrias
- The Porphyrias: Introduction
- Porphyrin-Heme Biosynthesis
- Classification of the Porphyrias
- Non-Acute and Acute Porphyrias
- The Non-Acute Porphyrias
- The Acute Porphyrias
- Confirmation of a Suspected Diagnosis of Porphyria
- Dual Porphyrias
- Abnormal Porphyrin Profile and Sideroblastic Anemia
- Molecular Genetic Research Strategies for the Porphyrias
- Animal Models and Future Options for Gene Therapy
- Conclusions and Future Prospects
- References
Amyloidosis and the Skin
Systemic Autoinflammatory Diseases
Xanthomatoses and Lipoprotein Disorders
- Xanthomas
- Lipoproteins and Their Metabolism
- Familial Chylomicronemia Syndrome (Frederickson Type I Hyperlipidemia)
- Hypercholesterolemia (Frederickson Type II Hyperlipidemia)
- Defective Metabolism of Lipoprotein Remnants
- Multifactorial Hyperlipidemias
- Xanthomatoses Without Elevated Serum Lipids
- Special Considerations
- Acknowledgment
- References
Fabry Disease
Lipoid Proteinosis
Cutaneous Mineralization and Ossification
Heritable Disorders of Connective Tissue with Skin Changes
Hereditary Disorders of Genome Instability and DNA Repair
Tuberous Sclerosis Complex
The Neurofibromatoses
Ectodermal Dysplasias
- Ectodermal Dysplasias: Introduction
- Hypohidrotic Ectodermal Dysplasia (Anhidrotic Ectodermal Dysplasia, Christ-Siemens-Touraine Syndrome; OMIM #305100)
- Hidrotic Ectodermal Dysplasia (Clouston Syndrome; OMIM #129500)
- Ankyloblepharon Filiforme Adnatum-Ectodermal Dysplasia-Cleft Palate Syndrome (Hay-Wells Syndrome; OMIM #106260)
- Ectrodactyly Ectodermal Dysplasia–Cleft Lip/Palate Syndrome; Split Hand–Split Foot–Ectodermal Dysplasia–Cleft Lip/Palate Syndrome (OMIM #604292)
- Rapp-Hodgkin Syndrome (OMIM #129400)
- Tooth and Nail Syndrome (Witkop Syndrome; Hypodontia with Nail Dysgenesis; OMIM #189500)
- Focal Dermal Hypoplasia of Goltz (OMIM #305600)
- Ectodermal Dysplasia with Skin Fragility
- Kindler Syndrome
- References
Genetic Immunodeficiency Diseases
Hematologic Diseases
Cutaneous Lymphoma
Inflammatory Diseases that Simulate Lymphomas: Cutaneous Pseudolymphomas
Langerhans Cell Histiocytosis
Non–Langerhans Cell Histiocytosis
- Non–Langerhans Cell Histiocytosis: Introduction
- Epidemiology
- Etiology and Pathogenesis
- History
- Juvenile Xanthogranuloma
- Generalized Eruptive Histiocytosis
- Progressive Nodular Histiocytosis
- Xanthoma Disseminatum
- Multicentric Reticulohistiocytosis
- Necrobiotic Xanthogranuloma
- Sinus Histiocytosis with Massive Lymphadenopathy (Rosai-Dorfman Disease)
- Treatment
- Prevention
- References
Biology of Mast Cells and the Mastocytosis Syndromes
The Skin and Disorders of the Alimentary Tract, the Hepatobiliary System, Kidney, and Cardiopulmonary System
Diabetes Mellitus and Other Endocrine Diseases
- Diabetes Mellitus
- Cutaneous Disorders of Diabetes Mellitus Associated with Metabolic, Vascular, Neurologic, or Immunologic Abnormalities
- Disorders Associated with Diabetes Mellitus But of Unknown Pathogenesis
- Thyroid Disease
- Parathyroid Disease
- Disorders of the Adrenal Gland
- Estrogen and Progesterone
- Androgenic Hormones
- Disorders of Growth Hormone
- References
Sarcoidosis
Cutaneous Manifestations of Internal Malignant Disease: Cutaneous Paraneoplastic Syndromes
Mechanisms of Autoimmune Disease
Lupus Erythematosus
Dermatomyositis
Scleroderma (Systemic Sclerosis)
Scleredema and Scleromyxedema
Relapsing Polychondritis
Rheumatoid Arthritis, Rheumatic Fever, and Gout
Sjögren Syndrome
Endothelium in Inflammation and Angiogenesis
Cutaneous Necrotizing Venulitis
Systemic Necrotizing Vasculitis
Erythema Elevatum Diutinum
Adamantiades-Behçet Disease
Kawasaki Syndrome
Pigmented Purpuric Dermatoses
Cryoglobulinemia and Cryofibrinogenemia
Raynaud Phenomenon
Malignant Atrophic Papulosis (Degos Disease)
Vascular Malformations
Cutaneous Changes in Peripheral Vascular Arterial Disease
Cutaneous Changes in Venous and Lymphatic Insufficiency
General Considerations of Bacterial Diseases
Superficial Cutaneous Infections and Pyodermas
Gram-Positive Infections Associated with Toxin Production
Soft-Tissue Infections: Erysipelas, Cellulitis, Gangrenous Cellulitis, and Myonecrosis
Gram-Negative Coccal and Bacillary Infections
- Gram-Negative Coccal and Bacillary Infections: Introduction
- Infections Due to Neisseria meningitidis (Meningococcus)
- Infections Due to Pseudomonas aeruginosa
- Skin Infections Due to Other Pseudomonas Species
- Infections Due to Haemophilus influenzae
- Cutaneous Manifestations of Salmonella Infections (Enteric Fever)
- Infections with Other Gram-Negative Bacilli that Have Cutaneous Manifestations
- References
The Skin in Infective Endocarditis, Sepsis, Septic Shock, and Disseminated Intravascular Coagulation
Bartonellosis
Miscellaneous Bacterial Infections with Cutaneous Manifestations
- Miscellaneous Bacterial Infections with Cutaneous Manifestations: Introduction
- Anthrax
- Tularemia (Francisella Tularensis Infections)
- Plague
- Brucellosis
- Glanders
- Pasteurella multocida Infections
- Rat-Bite Fever
- Seal Finger
- Listeriosis (Listeria monocytogenes Infections)
- Vibrio vulnificus Infections
- Other Cutaneous Vibrio Infections
- Aeromonas hydrophila Infections
- Melioidosis
- Erysipeloid
- Streptococcus iniae Infections
- Chromobacterium Violaceum Infections
- Leptospirosis
- Diphtheria
- Other Cutaneous Diphtheroid Infections
- References
Tuberculosis and Infections with Atypical Mycobacteria
- Tuberculosis and Infections with Atypical Mycobacteria: Introduction
- Classification of Mycobacteria
- Mycobacteria and the Acquired Immunodeficiency Syndrome Pandemic
- Tuberculosis of the Skin
- Skin Diseases Caused by Mycobacterium tuberculosis/bovis Infection
- The Tuberculids
- Treatment of Cutaneous Tuberculosis
- Diseases Caused by Mycobacteria Other Than M. tuberculosis
- References
Actinomycosis, Nocardiosis, and Actinomycetoma
Leprosy
Lyme Borreliosis
Superficial Fungal Infection: Dermatophytosis, Onychomycosis, Tinea Nigra, Piedra
Yeast Infections: Candidiasis and Tinea (Pityriasis) Versicolor
Deep Fungal Infections
Viral Diseases: General Considerations
Exanthematous Viral Diseases
Herpes Simplex
Varicella and Herpes Zoster
Poxvirus Infections
Warts
Human Retroviral Disease: Human T-Lymphotropic Viruses
Cutaneous Manifestations of Human Immunodeficiency Virus Disease
The Rickettsioses, Ehrlichioses, and Anaplasmoses
Syphilis
Endemic (Non-Venereal) Treponematoses
- Endemic (Non-Venereal) Treponematoses: Introduction
- Pinta (Carate, Mal De Pinta, Azul)
- Yaws (Framboesia Tropica, Pian, Buba, Paru, Parangi)
- Endemic Syphilis (Bejel, Firjal, Belesh, Njovera)
- Diagnosis of the Non-Venereal Treponematoses
- Histopathologic Features of the Non-Venereal Treponematoses
- Treatment of the Non-Venereal Treponematoses
- Epidemiologic Perspective
- References
Chancroid
Lymphogranuloma Venereum
Granuloma Inguinale
Gonorrhea and Other Venereal Diseases
Leishmaniasis and Other Protozoan Infections
Helminthic Infections
Scabies, Other Mites, and Pediculosis
Bites and Stings of Terrestrial and Aquatic Life
Arthropod Bites and Stings
Occupational Skin Diseases Due to Irritants and Allergens
- Occupational Skin Diseases Due to Irritants and Allergens: Introduction
- Historical Aspects and Resources
- Epidemiology
- Irritant Contact Dermatitis
- Allergic Contact Dermatitis
- Contact Urticaria and Immediate Contact Reactions
- Diagnosis of Occupational Skin Disease
- Treatment and Prevention
- Prognosis and Persistence
- Impairment and Disability Evaluation
- Health Risk Assessment
- References
Occupational Noneczematous Skin Diseases Due to Biologic, Physical, and Chemical Agents
Cutaneous Manifestations of Biologic, Chemical, and Radiologic Terrorism Attacks
Principles of Topical Therapy
Pharmacokinetics and Topical Applications of Drugs
Topical Corticosteroids
Topical Retinoids
- Topical Retinoids: Introduction
- Retinoid Receptors
- Receptor-Selective Retinoids
- Retinoid Receptors in Human Skin
- Retinoid Target Genes and Their Activation Cascade in Human Skin
- Pharmacology: Nomenclature
- Clinical Use
- Dosage Schedules and Forms
- Adverse Effects
- Drug Interaction and Incompatibilities
- References
Topical Antibiotics
Topical Antifungal Agents
Topical and Intralesional Cytotoxic Agents
Topical Immunomodulators
Other Topical Medications
Photoprotection and Sun Protective Agents
Special Considerations for Topical Therapy of Ethnic Skin
Systemic Glucocorticoids
Dapsone
Aminoquinolines
Cytotoxic and Antimetabolic Agents
Retinoids
Antihistamines
Antibiotics
Antiviral Drugs
Oral Antifungal Agents
Immunosuppressive and Immunomodulatory Drugs
Immunobiologicals, Cytokines, and Growth Factors in Dermatology
Anti-Angiogenic Agents
Drug Interactions
Therapeutic Photomedicine: Phototherapy
Photochemotherapy and Photodynamic Therapy
Lasers and Flashlamps in Dermatology
Radiotherapy
Complementary and Alternative Medicine in Dermatology
Dermatologic Surgery: Introduction to Anatomy and Approach
Excisional Surgery and Repair, Including Flaps and Grafts
Mohs Micrographic Surgery
Nail Surgery
Cryosurgery and Electrosurgery
Surgical Complications
Wound Repair: Mechanisms and Practical Considerations
- Wound Repair: Mechanisms and Practical Considerations: Introduction
- Phases of Wound Healing
- Extracellular Matrix Proteins
- Moist Wound Healing and the Repair Process
- Wound Healing of Skin Grafts
- Chronic Wounds and Impaired Healing
- Other Therapies for Impaired Healing
- Predicting Wound Closure
- Summary
- References
Treatment for Varicose and Telangiectatic Leg Veins
Cosmetics and Skin Care in Dermatology
- Cosmetics and Skin Care in Dermatology: Introduction
- Skin Hydration
- Skin Sensitivity and Cosmetic Intolerance Syndrome
- Skin Irritation and Allergy Due to Cosmetics and Skin Care Products
- Other Skin Reactions Due to Cosmetics
- Skin Reactions Due to Fragrances
- Skin Reactions Due to Preservatives
- Skin Pigmentation
- Skin Aging: Wrinkled versus Tight
- Combinations of Skin Types
- Conclusion
- References
Skin Resurfacing: Ablative Lasers, Chemical Peels, and Dermabrasion
Cosmetic Applications of Non-Ablative Lasers and Other Light Devices
Liposuction
Soft-Tissue Augmentation
Botulinum Toxin
Hair Transplantation and Alopecia Reduction
Topics within this title:
- Abnormalities
- Acantholysis
- Acanthoma
- Acanthosis Nigricans
- Acne
- Acne Vulgaris
- Acneiform Eruptions
- Acrodermatitis
- Acromegaly
- Actinic Dermatitis
- Actinomycosis
- Acute Intermittent Porphyria
- Acute Porphyrias
- Addison Disease
- Adenocarcinoma
- Adenoma
- Adhesion
- Adult Progeria
- Adult T-Cell Leukemia
- Agammaglobulinemia
- AIDS
- Ainhum
- Albinism
- Aldrich Syndrome
- Alkaptonuria
- Allergic Contact Dermatitis
- Alopecia
- Alopecia Areata
- Amebiasis
- American Trypanosomiasis
- Amyloidosis
- Anaplasmoses
- Anemia
- Angioedema
- Angiolipoma
- Angioma
- Angiosarcoma
- Anhidrotic Ectodermal Dysplasia
- anomalies
- Anthrax
- Antibody
- Antigen
- Arteriovenous Malformations
- Arthritis
- Ascariasis
- Ataxia
- Atherosclerosis
- Atopic Dermatitis
- Atopic Eczema
- Autoimmune Disease
- B-Cell Lymphoma
- B-Cell Lymphomas
- Bacteremia
- Bacterial Endocarditis
- Bacterial Infection
- Bacterial Infections
- Bacterial Vaginosis
- Balanitis
- Bartonellosis
- Basal Cell Carcinoma
- Basal Cell Carcinomas
- Basal Cell Nevus Syndrome
- Bejel
- Benign Neoplasms
- Biliary Cirrhosis
- Bite
- Bites and Stings
- Blastomycosis
- Bloom Syndrome
- Blue Nevus
- Bowen Disease
- Branchial Cleft Cyst
- Branchial Cyst
- Brucellosis
- Buerger Disease
- Bullous Pemphigoid
- Burns
- Cancer
- Candidiasis
- Carbuncles
- Carcinoma
- Carcinoma in Situ
- Carcinomas
- Castleman Disease
- Cat-Scratch Disease
- Cellulitis
- Cerebrotendinous Xanthomatosis
- Cestode Infections
- Chancre
- Chancroid
- Cholestasis
- Chromoblastomycosis
- Chromomycosis
- Chronic Actinic Dermatitis
- Chronic Granulomatous Disease
- Cicatricial Pemphigoid
- Cirrhosis
- Clear Cell Acanthoma
- Cleft Lip
- Cleft Palate
- Clouston Syndrome
- Coccidioidomycosis
- Cockayne Syndrome
- Common Variable Immunodeficiency
- Congenital Disorders
- Congenital Syphilis
- Contact Dermatitis
- Corns
- Cryoglobulinemia
- Cryptococcosis
- Cushing Syndrome
- Cutaneous Larva Migrans
- Cutaneous Leishmaniasis
- Cutaneous T-Cell Lymphoma
- Cutaneous T-Cell Lymphomas
- Cutaneous Tuberculosis
- Cutis Laxa
- Cylindroma
- Cyst
- Cysticercosis
- Cysts
- Cytomegalovirus Infection
- Cytomegalovirus Infections
- Dedifferentiated Liposarcoma
- Deep Vein Thrombosis
- Delayed Hypersensitivity
- Dermatitis
- Dermatitis Herpetiformis
- Dermatofibrosarcoma
- Dermatomyositis
- Dermatophytoses
- Dermatophytosis
- Dermatoses
- Dermatosis
- Dermoid
- Dermoid Cyst
- Diabetes
- Diabetes Mellitus
- DiGeorge Syndrome
- Diphtheria
- Dirofilariasis
- Dracunculiasis
- Drug Abuse
- Drug Eruptions
- Ductal Carcinoma
- Dysbetalipoproteinemia
- Dyskeratosis Congenita
- Echinococcosis
- Ectodermal Dysplasia
- Ectodermal Dysplasias
- Eczema
- Ehrlichioses
- Embolism
- Endocarditis
- Endocrine Diseases
- Enterobiasis
- Eosinophilia
- Epidermoid Cyst
- Epidermolysis Bullosa
- Epidermolysis Bullosa Acquisita
- Epidermolysis Bullosa Simplex
- Epithelioid Sarcoma
- Erysipelas
- Erysipeloid
- Erythema
- Erythema Infectiosum
- Erythema Multiforme
- Erythemas
- Erythermalgia
- Erythrasma
- Erythroderma
- Erythromelalgia
- Erythroplasia
- Erythropoietic Porphyria
- Erythropoietic Protoporphyria
- Exanthem
- Exfoliative Dermatitis
- Extramammary Paget Disease
- Fabry Disease
- Familial Hypertriglyceridemia
- Familial Mediterranean Fever
- Fanconi Anemia
- Fascioliasis
- Favus
- Fever
- Fevers
- Fibroadenoma
- Fibrous Histiocytoma
- Filariasis
- Fistula
- Flushing
- Focal Dermal Hypoplasia
- Folliculitis
- Fox-Fordyce Disease
- Frostbite
- Furuncles
- Genome Instability
- Gianotti-Crosti Syndrome
- Glanders
- Gonorrhea
- Gout
- Graft-Versus-Host Disease
- Granular Cell Tumor
- Granuloma
- Granuloma Annulare
- Granuloma Inguinale
- Growth Disorders
- Hailey-Hailey Disease
- Hamartoma
- Hamartomas
- Hemangiomas
- Hematologic Diseases
- Hematologic Neoplasm
- Hepatoerythropoietic Porphyria
- Hereditary Coproporphyria
- Herpangina
- Herpes Gestationis
- Herpes Simplex
- Herpes Zoster
- Herpesvirus Infections
- Hibernoma
- Hidradenitis
- Hidradenoma
- Hidrocystoma
- Hidrotic Ectodermal Dysplasia
- Hirsutism
- Histiocytoma
- Histiocytosis
- Histoplasmosis
- Homocystinuria
- Hydroa Vacciniforme
- Hypercholesterolemia
- Hypereosinophilic Syndromes
- Hyperhidrosis
- Hyperlipidemia
- Hyperlipidemias
- Hypermelanoses
- Hyperplasia
- Hyperplasias
- Hypersensitivity
- Hyperthyroidism
- Hypertrichosis
- Hypertriglyceridemia
- Hypertrophic Scars
- Hypodontia
- Hypomelanoses
- Hypothyroidism
- Ichthyoses
- Impetigo
- Irritant Dermatitis
- Jaundice
- Juvenile Xanthogranuloma
- Kaposi Sarcoma
- Keloids
- Keratoacanthoma
- Keratoses
- Keratosis
- Kimura Disease
- Large Cell Lymphoma
- Larva Migrans
- Latent Syphilis
- Leiomyoma
- Leiomyosarcoma
- Leishmaniasis
- Lentigo
- Leprosy
- Leptospirosis
- Leukemia
- Leukoplakia
- Lichen Nitidus
- Lichen Planus
- Lichen Sclerosus
- Lichen Simplex Chronicus
- Lipodystrophies
- Lipodystrophy
- Lipoma
- Lipomatosis
- Liposarcoma
- Livedo Reticularis
- Loiasis
- Lupus
- Lupus Vulgaris
- Lyme Borreliosis
- Lyme Disease
- Lymphadenopathy
- Lymphatic Filariasis
- Lymphedema
- Lymphocytoma
- Lymphogranuloma Venereum
- Lymphoma
- Lymphomas
- Lymphomatoid Papulosis
- Madura Foot
- Maduromycosis
- Malignant Mixed Tumor
- Malnutrition
- Marfan Syndrome
- Mastocytosis
- Measles
- Mediterranean Spotted Fever
- Melanocytic Nevi
- Melanoma
- Melioidosis
- Meningitis
- Merkel Cell Carcinoma
- Metastases
- Metastasis
- Molluscum Contagiosum
- Monkeypox
- Morphea
- Mouth Disease
- Mucinous Carcinoma
- Multiple Endocrine Neoplasia
- Mycetoma
- Mycoses
- Mycosis Fungoides
- Myxoma
- Necrobiosis
- Necrobiosis Lipoidica
- Necrosis
- Neoplasm
- Neoplasms
- Nerve Sheath Myxoma
- Nerve Sheath Neoplasms
- Nerve Sheath Tumors
- Neuralgia
- Neurofibroma
- Neurofibromatoses
- Neurofibromatosis
- Neurofibromatosis Type 1
- Neurologic Findings
- Neurologic Manifestations
- Neuroma
- Neuromas
- Neurothekeoma
- Nevi
- Nevus
- North American Blastomycosis
- Ocular Rosacea
- Onchocerciasis
- Onychomycosis
- Orf
- Oroya Fever
- Osteogenesis Imperfecta
- Osteoporosis
- Pain
- Panniculitis
- Papillary Adenoma
- Paracoccidioidomycosis
- Paragonimiasis
- Paraneoplastic Syndromes
- Parapsoriasis
- Parathyroid Disease
- Pediculosis
- Pemphigoid
- Pemphigus
- Perioral Dermatitis
- Phenylketonuria
- Phlebitis
- Photoallergy
- Phototoxicity
- Piedra
- Pilar Cyst
- Pinta
- Pityriasis
- Pityriasis Lichenoides
- Pityriasis Rosea
- Pityriasis Rubra Pilaris
- Plague
- Pleomorphic Lipoma
- Pleomorphic Liposarcoma
- Poisoning
- Porokeratosis
- Porphyria
- Porphyria Cutanea Tarda
- Porphyrias
- Postoperative Complications
- Poxvirus Infections
- Primary Biliary Cirrhosis
- Progeria
- Protein-Energy Malnutrition
- Protozoan Infections
- Prurigo
- Pruritus
- Pseudolymphomas
- Pseudoxanthoma Elasticum
- Psoriasis
- Psoriatic Arthritis
- Purpura
- Pyoderma
- Pyoderma Gangrenosum
- Pyodermas
- Rabies
- Raynaud Phenomenon
- Reactive Arthritis
- Relapsing Polychondritis
- Rhabdomyoma
- Rhabdomyosarcoma
- Rheumatic Fever
- Rheumatism
- Rheumatoid Arthritis
- Rickettsialpox
- Rocky Mountain Spotted Fever
- Rosacea
- Rosai-Dorfman Disease
- Rotavirus
- Rothmund-Thomson Syndrome
- Rubella
- Sarcoidosis
- Sarcoma
- Scabies
- Scar
- Scarlet Fever
- Scars
- Schistosomiasis
- Schwannoma
- Sclerosis
- Scrofuloderma
- Scrub Typhus
- Seborrheic Dermatitis
- Seborrheic Keratosis
- Sepsis
- Septic Shock
- Septicemia
- Severe Combined Immunodeficiency
- Sexually Transmitted Diseases
- Shock
- Signs and Symptoms
- Sinus Histiocytosis
- Skin Disease
- Skin Diseases
- Skin Manifestations
- Smallpox
- Sneddon-Wilkinson Disease
- South American Blastomycosis
- Sparganosis
- Spider Veins
- Spindle Cell Nevus
- Spitz Nevus
- Sporotrichosis
- Squamous Cell Carcinoma
- Squamous Cell Carcinomas
- Staphylococcal Skin Infections
- Stevens-Johnson Syndrome
- Stings
- Streptococcal Infections
- Strongyloidiasis
- Subacute Bacterial Endocarditis
- Sweet Syndrome
- Syndrome
- Syndromes
- Syphilis
- Syringoma
- Systemic Lupus Erythematosus
- Systemic Sclerosis
- T-Cell Leukemia
- T-Cell Lymphoma
- T-Cell Lymphomas
- Tangier Disease
- Telangiectasia
- Thromboangiitis Obliterans
- Thrombosis
- Thyroid Disease
- Tinea
- Tinea Capitis
- Tinea Favosa
- Tinea Pedis
- Torulosis
- Toxic Epidermal Necrolysis
- Toxic Shock
- Toxicity
- Trench Fever
- Trichinosis
- Trypanosomiasis
- Tuberculid
- Tuberculids
- Tuberculosis
- Tuberous Sclerosis
- Tularemia
- Tumor
- Tumors
- Typhus
- Tyrosinemias
- Ulcer
- Ulcers
- Urticaria
- Vaccinia
- Varicella
- Varicose Veins
- Variegate Porphyria
- Variola
- Vasculitis
- Venereal Diseases
- Venous Thrombosis
- Verruga Peruana
- Vesicular Palmoplantar Eczema
- Viral Diseases
- Virus
- Virus Disease
- Vitamin A Deficiency
- Vitiligo
- Warts
- Werner Syndrome
- Wiskott-Aldrich Syndrome
- Xanthoma
- Xanthoma Disseminatum
- Xanthomas
- Xanthomatoses
- Xanthomatosis
- Xeroderma
- Xeroderma Pigmentosum
- Yaws
- Zoster