NUCLEAR CARDIOLOGY

Author: Gary Heller, MD, PhD, April Mann, BA, CNMT, NCT, RT(N), Robert Hendel, MD, FACC, FAHA, FASNC
Affiliation: UNIV OF CONN SCH OF MED
Publisher: McGraw-Hill
Publication Date: 2009
ISBN 10: 0071464751
ISBN 13: 9780071464758
Edition: 2nd

Description:

This well-illustrated guide offers a comprehensive look at the principles and techniques behind myocardial perfusion imaging, including instrumentation and cameras, general considerations, radiopharmaceuticals, and radiation safety and regulatory issues.

Table of Contents

Front Matter

  • ABOUT
  • Notice
  • DEDICATION
  • Contributors
  • Preface

SECTION 1 CAMERA AND INSTRUMENTATION

    SPECT Instrumentation

    • HISTORY
    • CRYSTAL
    • PHOTOMULTIPLIER TUBE
    • ELECTRONICS
    • COLLIMATION
    • SPECT SYSTEMS
    • IMAGE RECONSTRUCTION
    • SPECT QUALITY CONTROL
    • ACCEPTANCE TESTING
    • ANNUAL QUALITY CONTROL
    • REFERENCES

    Positron Emission Tomography Instrumentation

    • INTRODUCTION
    • PET RADIOTRACERS
    • PET DETECTORS
    • TYPES OF EVENTS
    • TEMPORAL SORTING OF DATA
    • AXIAL DATA
    • IMAGE RECONSTRUCTION
    • CORRECTIONS
    • NOISE-EQUIVALENT COUNT RATE
    • FACTORS AFFECTING SPATIAL RESOLUTION
    • PARTIAL VOLUME EFFECTS
    • SUMMARY
    • ACKNOWLEDGMENT
    • REFERENCES

SECTION 2 RADIOPHARMACEUTICALS

    Basic Principles of Flow Tracers

    • INTRODUCTION
    • TRACER KINETICS
    • CHARACTERISTICS OF FLOW TRACERS
    • TRACER RETENSION
    • TRACER DISTRIBUTION
    • TRACER CLEARANCE
    • SUMMARY
    • REFERENCES

    PET Radiopharmaceuticals

    • INTRODUCTION TO PET IMAGING
    • POSITRON EMISSION AND ANNIHILATION IMAGING
    • PET RADIOTRACERS
    • FLUORINE-18
    • GLUCOSE METABOLISM
    • VIABILITY PROTOCOL
    • RUBIDIUM-82
    • NITROGEN-13 AMMONIA
    • CARBON-11
    • SUMMARY
    • REFERENCES

    Fatty Acid Metabolic SPECT Imaging: Applications in Nuclear Cardiology

    • FATTY ACID RADIOPHARMACEUTICALS
    • KINETICS OF BMIPP
    • IMAGING BMIPP
    • ACQUISITION PROTOCOLS
    • POTENTIAL CLINICAL APPLICATIONS
    • Fatty Acid Imaging for Prediction of Left Ventricular Functional Recovery After Acute Myocardial Infarction
    • REFERENCES

    Cardiac Neuronal Imaging with 123 I- m IBG

    • INTRODUCTION
    • IMAGING OF SYMPATHETIC NERVE TERMINALS
    • PROCEDURE FOR 123 I- m IBG ADMINISTRATION
    • PROCEDURE FOR 123 I- m IBG IMAGING
    • IMAGE ANALYSIS AND INTERPRETATION
    • EXTRANEOUS CONDITIONS THAT AFFECT m IBG IMAGING
    • NEURONAL TRACERS FOR PET
    • CONCLUSION
    • REFERENCES

SECTION 3 PRINCIPLES AND TECHNIQUE CONSIDERATIONS FOR STRESS TESTING

    Exercise Testing

    • INTRODUCTION
    • INDICATIONS
    • EXERCISE PHYSIOLOGY
    • PERFORMING THE EXERCISE STRESS TEST
    • INTERPRETATION OF THE STRESS TEST
    • REFERENCES

    Pharmacologic Stress Testing in Myocardial Perfusion Imaging: Technical Application

    • INTRODUCTION
    • DOBUTAMINE SRESS
    • VASODILATOR (ADENOSINE AND DIPYRIDAMOLE) STRESS MPI
    • COMBINED VASODILATOR AND EXERCISE STRESS TESTING
    • SELECTIVE ADENOSINE A2A RECEPTOR AGONISTS
    • SUMMARY
    • REFERENCES

SECTION 4 SPECT MYOCARDIAL PERFUSION IMAGING TECHNIQUES

    Protocols and Acquisition Parameters for SPECT Myocardial Perfusion Imaging

    • INTRODUCTION
    • IMAGING PROTOCOLS
    • CAMERA CONSIDERATIONS
    • ACQUISITION CONSIDERATIONS
    • CONCLUSION
    • REFERENCES

    Myocardial SPECT Processing

    • INTRODUCTION
    • IMAGE FILTERING
    • IMAGE RECONSTRUCTION
    • IMAGE REORIENTATION
    • QUANTITATIVE ANALYSIS
    • SAMPLING THE MYOCARDIUM
    • TECHNOLOGIST CONTRIBUTION
    • CONCLUSION
    • ACKNOWLEDGMENT
    • REFERENCES

    Technical Considerations in Quantifying Myocardial Perfusion and Function

    • INTRODUCTION
    • MYOCARDIAL PERFUSION
    • MYOCARDIAL FUNCTION
    • CONCLUSION
    • REFERENCES

    Artifacts and Quality Control for Myocardial Perfusion SPECT Including Attenuation Correction

    • INTRODUCTION
    • QUALITY CONTROL SPECIFIC TO ATTENUATION CORRECTION
    • SUMMARY
    • REFERENCES

SECTION 5 MYOCARDIAL PERFUSION IMAGING PET TECHNIQUES

    Positron Emission Tomographic Techniques and Procedures: Myocardial Perfusion Imaging

    • SPACE DESIGN
    • PATIENT PREPARATION FOR PET PERFUSION ASSESSMENT
    • STRESS TESTING PROTOCOLS FOR PET
    • ACQUISITION PROTOCOLS
    • IMAGE QUALITY CONTROL/ARTIFACT RECOGNITION
    • NORMAL AND ABNORMAL SCAN APPEARANCES
    • REFERENCES

    PET for Assessing Myocardial Viability

    • METHODOLOGY FOR ASSESSING MYOCARDIAL VIABILITY WITH PET
    • CONCLUSIONS
    • REFERENCES

    Attenuation and Scatter Correction in Cardiac PET

    • INTRODUCTION
    • BASIC PHYSICS OF ATTENUATION IN PET
    • ATTENUATION CORRECTION IN PET
    • OBTAIN ATTENUATION ESTIMATE
    • CORRECTION FOR SCATTER IN PET
    • CHALLENGES FOR ATTENUATION AND SCATTER CORRECTION IN PET
    • REFERENCES

SECTION 6 CARDIAC COMPUTERIZED TOMOGRAPHY

    Fundamentals of Computed Tomography and Computed Tomography Angiography

    • PHYSICS OF CT
    • DISPLAY OF CT DATA
    • QUALITY CONTROL
    • COMMON PROCEDURES
    • CORONARY CTA
    • IMAGE ACQUISITION SETUP
    • INTERPRETATION
    • DIAGNOSTIC ACCURACY STUDIES
    • PERIPHERAL VASCULAR STUDIES
    • FUTURE DIRECTIONS
    • CONCLUSION
    • REFERENCES

SECTION 7 IMAGING VENTRICULAR FUNCTION

    Technical Aspects of Scintigraphic Evaluation of Ventricular Function

    • INTRODUCTION
    • QUALITY PERFORMANCE IN IMAGE ACQUISITION AND PROCESSING
    • REFERENCES

    ECG-Gated SPECT Imaging

    • OVERVIEW OF GATED SPECT
    • ACQUSITION OF GATED SPECT IMAGES
    • IMAGE PROCESSING
    • GATED SPECT WITH THALLIUM-201
    • FUTURE DIRECTIONS
    • REFERENCES

    Planar and SPECT Equilibrium Radionuclide Angiography

    • EQUILIBRIUM RADIONUCLIDE ANGIOGRAPHY
    • RADIOPHARMACEUTICALS AND RADIOLABELING
    • IMAGE ACQUISITON AND PROCESSING
    • VISUAL ASSESSMENT OF IMAGES
    • QUANTITATIVE ASSESSMENT OF IMAGES
    • SPECT ERNA
    • SUMMARY
    • REFERENCES

SECTION 8 RADIATION SAFETY AND REGULATORY ISSUES

    Radiation Safety

    • UNITS OF RADIATION MEASUREMENT
    • RADIATION SAFETY INSTRUMENTS
    • RADIATION SAFETY CONSIDERATIONS FOR THE TECHNOLOGIST
    • RADIATION SAFETY FROM THE STANDPOINT OF THE PATIENT
    • RADIATION PROTECTION IN PET
    • REGULATION OF THE NUCLEAR MEDICINE LABORATORY
    • CONCLUSION
    • REFERENCES

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